Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Phosphorus or phosphorus compound
Patent
1996-10-16
2000-09-12
Levy, Neil S.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Phosphorus or phosphorus compound
424484, 623 16, 423308, 423311, 106690, A61K 4702
Patent
active
061174564
ABSTRACT:
The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature an is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing.
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Otsuk
Aiolova Maria
Lee Dosuk D.
Rey Christian
Tofighi Aliassghar
Etex Corporation
Levy Neil S.
Scozzafava Mary Rose
LandOfFree
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