Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-12-22
2011-10-04
Angell, J. E. (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S001000
Reexamination Certificate
active
08030286
ABSTRACT:
Methods are provided to increase resistance to cell damage in a subject. The increase in resistance to cell damage in a subject in the subject is accomplished by decreasing activity of eEF2 kinase in the subject. The eEF2 kinase activity can be decreased by decreasing the amount of functional eEF2 kinase produced by the subject, including contacting the eEF2 kinase with a compound that inhibits phosphorylation of eEF2 kinase substrate or decreasing the amount of functional eEF2 kinase is decreased by reducing expression of a gene encoding the eEF2 kinase.
REFERENCES:
patent: 6624170 (2003-09-01), Giovanella et al.
patent: 2002/0142429 (2002-10-01), Ryazanov et al.
Chu Hsueh-Ping
Ryazanov Alexey G.
Angell J. E.
Fox Rothschild LLP
University of Medicine and Dentistry of New Jersey
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