Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-08-02
2011-10-11
Spector, Lorraine (Department: 1646)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S04400A, C530S300000, C530S350000
Reexamination Certificate
active
08034786
ABSTRACT:
The invention relates to the field of regulating metabolic processes, for example, to regulate the presence and/or activity of a receptor at the surface of a cell. The invention provides a method for controlling the presence of a receptor at the surface of a cell comprising interfering with the interaction of an F-box protein with a ubiquitin/proteasome binding site of the receptor, wherein the ubiquitin/proteasome binding site comprises particular amino acid sequences. The invention further provides a method for controlling the presence of a growth hormone receptor (GHR) at the surface of a cell comprising interfering with the interaction of an F-box protein with a ubiquitin/proteasome binding site of the GHR.
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patent: WO 99/46298 (1999-09-01), None
patent: WO 2007/015638 (2007-02-01), None
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PCT International Search Report, PCT/NL2006/000396, dated Feb. 13, 2007.
Strous Gerardus Jacobus Antonius Maria
Van Kerkhof Petrus Johannes Maria
Kaufman Claire
Recharge B.V.
Spector Lorraine
TraskBritt P.C.
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