Methods and materials relating to gene expression

Details Methods and materials relating to gene expression Methods and materials relating to gene expression

2000-12-20

2008-01-08

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C536S024100

Reexamination Certificate

active

07316914

ABSTRACT:
An expression cassette for expressing a nucleic acid of interest derived from the regulatory region of the methylenomycin gene cluster of the SCP1 plasmid ofStreptomyces coelicolorA3(2), and related materials and methods.

REFERENCES:
Chater et al. EMBO. 1985; 4:1893-5.
Neal et al. Gene. 1987; 58:229-41.
Redenbach et al. J. Bact. 1998; 180:2796-99.
Richards, F.M., 1997, Cell Mol. Life Sci 53:790-802.
Holstege et al., 2006, Cell 124: 21-23.
Onaka et al., 1997, J. Bacteriol. 179, 8: 2748-2752.
Aguilar A., Hopwood D. A. (1982) J. Gen. Microbiol 128: 1893-1901 “Determination of methylenomycin A synthesis by the pSV1 plasmid fromStreptomycesviolaceus-ruber SANK 95570”.
Alvarez, M. A., Chater K. F., Rodicio M. R. (1993) Mol. Microbiol. 8: 243-252 “Complex transcription of an operon encoding the Sall restriction-modification system ofSteptomyces albus G”.
Bruton, C. J., Guthrie E. P., Chater K. F. (1991) Bio/Technology 9: 652-656 “Phage vectors that allow monitoring of transcription of secondary metabolism genes inStreptomyces”.
Bruton C. J., Chater K. F. (1987) Nucl Acids Res 15: 7053-7065 “Nucleotide sequence of IS110, an insertion sequence ofStreptomyces coelicolorA3(2)”.
Database NCBI Accession No. AJ276673 Brutin C J (2000) “Streptomyces coelicolorpartial SCP1 plasmid including genes for methylenomycin biosynthesisl” XP002165370.
Bruton C., Woodburn L., Angel S., Chater K. (1990) 6thInternational Symposium on Genetics of Industrial Microorganisms GIM90 Abstract Book: Abstract A41 Strasbourg Palais des Congres Aug. 12-18, 1990 “ Structure and regulation of the methylenomycin biosynthetic genes ofStreptomyces coelicolorA3(2)”.
Caffrey P, Bevitt D J, Staunton J, Leadlay P F (1992) FEBS Let. 304: 225-228. “Identification of DEBS1, DEBS2 and DEBS3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase fromSaccharopolyspora erythraea”.
Chater, K. F., Bruton C. J., King A. A., Saurez J. E. (1982) Gene 19: 21-23. “The expression ofStreptomycesandEscherichia colidrug resistance determinants cloned into theStreptomycesphage ΦC31”.
Chater, K. F., Bruton C. J. (1983) Gene 26: 67-78. “Mutational cloning inStreptomycesand the isolation of antibiotic production genes”.
Chater, K. F. and C. J. Bruton. (1985) EMBO J. 4: 1893-1897 “Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered”.
Chater, K. F. (1990) Bio/Technology 8: 115-121 “The improving prospects for yield increase by genetic engineering in antibiotic-producingstreptomycetes”.
Fernandez-Moreno, M. A. (1991) Cell 66: 769-780. “The act cluster contains regulatory and antibiotic export genes, direct targets for control by the bldA tRNA gene ofStreptomyces”.
Fisher S. H., Bruton C. J., Chater K. F. (1987) Mol. Gen. Genet. 206: 35-44. “The glucose kinase gene ofStreptomyces coelicolorand its use in selecting spontaneous deletions for desired regions of the genome”.
Guilfoile P G et al (1992) J. Bacteriol. 174(11): 3651-3658 “Sequence and Transcriptional Analysis of theStreptomycesglaucescens tcmAR Tetracenomycin C resistance and repressor gene Loci”.
Guthrie, E. P., Chater K. F (1990) J. Bacteriol. 172 : 6189-6193 “The level of a transcript required for production of aStreptomyces coelicolorantibiotic is conditionally dependent on a tRNA gene”.
Hillen W., Berens C. (1994) Annu. Rev. Microbiol. 48 : 345-369 “Mechanisms underlying expression of Tn1O encoded tetracycline resistance”.
Hobbs, G., Obanye A. I. C., Petty J., Masson J. C., Barratt E., Gardner D. C. J., Flett F., Smith C. P., Broda P., Oliver S. G. (1992) J. Bacteriol. 174: 1487-1494 “An integrated approach to studying regulation of production of the antibiotic methylenomycin byStreptomyces coelicolorA3 (2)”.
Hopwood, D. A. (1997) Chem. Rev. 97: 2465-2497. “Genetic contributions to understanding polyketide synthases”.
Horinouchi, S., H. Suzuki, M. Nishiyama and T. Beppu. (1989) J. Bacteriol. 171: 1206-1210 “Nucleotide sequence and transcriptional analysis of theStreptomyces griseusgene (afsA) responsible for A-factor biosynthesis”.
Horinouchi S., Kumada Y., Beppu T. (1984) J. Bacteriol. 158: 481-487 “Unstable genetic determinant of A-factor biosynthesis instreptomycin-producing organisms: cloning and characterization”.
Hornemann, U., Hopwood D. A. (1978) Tetrahed. Lett. 33:2977-2978 Isolation and characterization of desepoxy-4,5-didehydro-methylenomycin A, a precursor of the antibiotic methylenomycin A in SCP1+strains ofStreptomyces coelicolorA3 (2).
Ingram C., Brawner M., Youngman P., Westpheling J. (1989) J. Bacteriol. 171: 6617-6624 “xyIE functions as an efficient reporter gene inStreptomycesspp.: use for the study of galP1, a catabolite-controlled promoter”.
Janssen, G. R., Bibb M. J. (1993) Gene 124: 133-134. “Derivatives of pUC18 that haveBglII sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening ofEscherichia colicolonies”.
Kirby, R., Hopwood D. A. (1977) J. Gen. Microbiol. 98: 239-252 “Genetic determination of methylenomycin synthesis by the SCP1 plasmid ofStreptomyces coelicolorA3 (2)”.
Kirby R., Wright L. F., Hopwood D. A. (1975) Nature 254: 265-267. “Plasmid-determined antibiotic synthesis and resistance inStreptomyces coelicolor”.
Lawlor E. J. (1987) PhD Thesis, University of Easr Anglia, UK “Molecular Genetics of bldA, a developmental gene ofStreptomyces coelicolor”.
Leskiw B., Guthrie E., Lawlor E., Daly B., Chater K. (1990) 6thInternational Symposium on Genetics of Industrial Microorganisms GIM90 Abstract Book: Abstract A43 Strasbourg Palais des Congres Aug. 12-18, 1990 “Differentiation and antibiotic production inStreptomyces coelicolorare regulated by a tRNA for a very rare codon”.
Leskiw B. K., Lawlor E. J., Fernandez-Abalos J. M. and Chater K. F. (1991) Proc. Natl. Acad. Sci. USA 88: 2461-2465. “TTA codons in some genes prevent their expression in a class of developmental, antibiotic-negativeStreptomycesmutants”.
MacNeil D. J., Gewain K. M., Ruby C. L., Dezeny G., Gibbons P. H., MacNeil T. (1992) Gene 111: 61-68. “Analysis ofStreptomyces avermitilisgenes required for avermectin biosynthesis utilizing a novel integration vector”.
DATABASE EMBL (1998) Accession No. AF072887 Moore R. A., DeShazer D., Reckseidler S., Weissman A., Woods D. E. “Burkholderia pseudomalleiregulator AmrR (amrR), putative membrane fusion protein AmrA (amrA), and putative transporter AmrB (amrB) genes, complete cds”.
Nakano H., Takehara E., Nihira T., Yamada Y. (1998) J. Bacteriol. 180: 3317-3322 “Gene replacement analysis of theStreptomyces virginiaebarA gene encoding the butyrolactone autoregulator receptor reveals that BarA acts as a repressor in virginiamycin biosynthesis”.
Neal R. J., Chater K. F. (1987) Gene 58: 229-241. “Nucleotide sequence analysis reveals similarities between protein determining methylenomycin A resistance inStreptomycesand tetracycline resistance ineubacteria”.
Onaka H., Horinouchi S. (1997) Mol. Microbiol. 24: 991-1000. “DNA-binding activity of the A-factor receptor protein and its recognition DNA sequences”.
Onaka H., Sugiyama M., Horinouchi S. (1997) J. Bacteriol. 179: 2748-2752. “A mutation at proline-115 in the A-factor receptor protein ofStreptomyces griseusabolishes DNA-binding ability but not ligand-binding ability”.
Onaka H., Nakagawa T., Horinouchi S. 1998 Mol. Microbiol. 28: 743-753. “Involvement of two A-factor receptor homologues inStreptomyces coelicolorA3 (2) in the regulation of secondary metabolism and morphogenesis”.
Onaka H., Ando N., Nihira T., Yamada Y., Beppu T., Horinouchi S. (1995) J. Bacteriol. 177: 6083-6092. “Cloning and char

Affiliated with

Also associated with

Rating

Methods and materials relating to gene expression does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and materials relating to gene expression, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and materials relating to gene expression will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3963381