Methods and materials for the induction of T cell anergy

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds specifically-identified oligosaccharide structure

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4241411, 4241561, 435 7021, 4351722, 43524027, 5303881, 5303875, 5303871, 53038885, 530809, 5303873, A61K 39395, C12N 512, C12P 2108, C07K 1618

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057470340

ABSTRACT:
Anti-B7-1 antibodies or other B7-1 ligands may be used to prevent or treat a T-cell-mediated immune system disease in a patient or to induce antigen-specific tolerance.
The anti-B7-1 antibodies may be used to cause T cell anergy, treat allograft transplant rejection, treat graft versus host disease, and prevent or treat rheumatoid arthritis. An immunosuppressive agent is co-administered with the antibody.

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