Methods and materials for producing gene libraries

Details Methods and materials for producing gene libraries Methods and materials for producing gene libraries

1996-12-20

1999-02-09

Degen, Nancy

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 911, 4351723, 4353201, 536 231, 536 234, C12N 1564, C12P 1934, C07H 2104

Patent

active

058692959

ABSTRACT:
Methods for producing libraries of diverse nucleotide sequences, and libraries of polypeptides encoded thereby, are provided. The nucleotide sequences comprise a first and a second constant region coupled to a coding sequence, wherein the coding sequence is formed by sequentially coupling nucleotides in a mixture of predetermined proportions of A, T, C, and G based upon a known amino acid profile. Libraries of vectors comprising the diverse nucleotide sequences are also provided. DNA and amino acid sequences encoding the libraries are further provided.

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