Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1995-02-15
1997-08-12
Fleisher, Mindy
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 911, 4353201, 536 231, 536 234, C12N 1564, C12P 1934, C07H 2104
Patent
active
056564678
ABSTRACT:
Methods for producing libraries of diverse nucleotide sequences, and libraries of polypeptides encoded thereby, are provided. The nucleotide sequences comprise a first and a second constant region coupled to a coding sequence, wherein the coding sequence is formed by sequentially coupling nucleotides in a mixture of predetermined proportions of A, T, C, and G based upon a known amino acid profile. Libraries of vectors comprising the diverse nucleotide sequences are also provided. DNA and amino acid sequences encoding the libraries are further provided.
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Butt Tauseef R.
LaBean Thomas H.
Degen Nancy J.
Fleisher Mindy
SmithKline Beecham Corporation
The Trustees of the University of Pennsylvania
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