Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2011-01-04
2011-01-04
Zhou, Shubo (Joe) (Department: 1631)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S004000, C435S007100, C514S002600, C702S019000
Reexamination Certificate
active
07862995
ABSTRACT:
The present invention relates to a panel of targeted therapy markers that can be used in assessing a particular subject's sensitivity to various therapeutic agents and cancer treatments as a means of prognosticating whether a treatment or use of a particular therapeutic agent will result in a clinically positive outcome. Cellular receptors, ligands to those receptors and molecules involved in the programmed cell death pathway are examples of targeted therapy markers that might be used in the present invention.
REFERENCES:
Smith et al., Br. J. Cancer, 2004, vol. 91, pp. 1190-1194, Aug. 10, 2004.
Cobleigh et al., Journal of Clinical Oncology, vol. 17, pp. 2639-2648, 1999.
Perissi et al., Oncogene, vol. 19, pp. 280-288, 2000.
Bamberger et al., Hormone Research, vol. 54, pp. 32-37, 2000.
Bacus Sarah S.
Hill Jason
K&L Gates LLP
Targeted Molecular Diagnostics
Zhou Shubo (Joe)
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