Methods and materials for improved high gradient magnetic separa

Details Methods and materials for improved high gradient magnetic separa Methods and materials for improved high gradient magnetic separa

1994-05-31

1996-08-06

Feisee, Lila

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

75255, 209213, 209214, 210222, 210691, 210695, 252 6251, 435 29, 435174, 435239, 435803, 436526, C12N 506

Patent

active

055432891

ABSTRACT:
Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. Superior superparamagnetic particles, optionally coated with a polysaccharide or other, usually organic, materials can be prepared in uniform compositions with homogeneous magnetizations. The coating can conveniently be conjugated to a specific binding moiety complementary to a biological material whose purification or separation is desired. In addition, plastic coated matrices which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS.

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