Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-06-21
2005-06-21
Duffy, Patricia A. (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007800, C435S007210, C436S518000
Reexamination Certificate
active
06908742
ABSTRACT:
Methods for determining levels of endotoxin in a sample are provided. These methods are useful in the diagnosis of septicemia. Kits for the detection of endotoxin are also provided.
REFERENCES:
patent: 5773306 (1998-06-01), Neely
Nagata, Y. and Shirakawa, K., “Seating standards for the levels of endotoxin in the embryo culture media of humanin vitrofertilization and embryo transfer”,Fertility and Sterility, 1996.
Akarasereenont et al., “Comparison of the induction of cycloooxygenase and nitric oxide synthase by endotoxin in endothelial cells and macrophages”,Eur. J. Pharmacol.1995.
Brigham et al., “Endotoxin and Lung Injury”,Am. Rev. Respir. Dis.1986, 133:913-927.
Bruns, R.F. “Adenosine Receptor Binding Assays”,Receptor Biochemistry and Methodology, vol. II: Adenosine Receptors, DMF Cooper and C. Londos (eds), Alan Liss, Inc., New York, NY, 1988, pp 43-62.
Kambayashi et al., “A novel endotoxin-specific assay by turbidimetry withLimulusamoebocyte lysate containing β-glucan”,J. Biochem. Biophys. Methods1991, 22:93-100.
Ku, H-H, et al., “Monoclonal Antibodies to Adenosine Receptor by an Auto-Anti-Idiotypic Approach”,J. Immunol.1987 139:2376-2384.
Jacobson et al., “Adenosine Receiptors: Pharmacology, Structure-Activity Relationships, and Therapeutic Potential”,J. Med. Chem.1992, 35:407-422.
“Increase in National Hospital Discharge Survery Rates for Septicemia—United States, 1979-1987”,MMWR1990, 39:31-34.
Minobe et al., “Assay of Endotoxin in Human Plasma Using Immobilized Histidine,LimulusAmoebocyte Lysate and Chromogenic Substrate”,Eur. J. Clin. Chem. Clin. Biochem.1994, 32:797-803.
Morita et al., “A New (1-3)β-D-Glucan-Mediated Coagulation Pathway Found inLimulusAmebocytes”,FEBS Letters1981 129:318-321.
Morrison, “Endotoxins and Disease Mechanisms”,Ann. Rev. Med.1987, 38:417-432.
Obayashi et al., “A new chromogenic endotoxin-specific assay using recombined limulus coagulation enzymes and its clinical applications”,Clinica Chimica Acta1985, 149:55-65.
Obayashi, T. J., “Addition of perchloric acid to blood samples for colorimetric limulus test using chromogenic substrate: Comparison with conventional procedures and clinical applications”,Lab. Clin.
Nawata et al., “Specific assay for endotoxin using immobilized histidine,Limulusamoebocyte lysate and a chromogenic substrate”,J. Chromatography1992, 597:415-424.
Pfeiffer, M. and Weiss, A.R, “Removal of Lal-test interfering low molecular weight substances by ultrafiltration”,Detection of Bacterial Endotoxin with the Limulus Amebocyte Lysate Test, WW.
Rietschel et al., “Bacterial endotoxin: molecular relationships of structure to activity and function”,FASEB J.1994, 8:217-225.
Schletter et al., “Molecular mechanisms of endotoxin activity”,Arch. Microbiol.1995, 164:383-389.
Thomas et al., “Quantitative endotoxin determination in blood with a chromogenic substrate”,Clinica Chimica Acta. 1981, 116:63-68.
Wessels et al., “Plasma endotoxin concentration in healthy primates and duringE. coli-induced shock”,Crit. Care Med. 1988 16:601-605.
Williams et al., “Ketoconazole inhibits alveolar macrophage production of inflammatory mediators involved in acute lung injury (adult respiratory distress syndrome)”,Surgery1992, 112:270-277.
Wright, “Multiple receptors for endotoxin”,Current Opinion in Immunol. 1991, 83-91.
Zhang et al., “Sensitive Quantitation of Endotoxin by Enzyme-Linked Immunosorbent Assay with Monoclonal Antibody againstLimulusPeptide C”,J. Clin. Microbiol. 1994, 32:416-422.
Duffy Patricia A.
Licata & Tyrrell P.C.
Trustees of the University of Pennsylvania
LandOfFree
Methods and kits for the detection of endotoxin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and kits for the detection of endotoxin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and kits for the detection of endotoxin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3512959