Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-11-08
2008-12-23
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
07468250
ABSTRACT:
Simple methods and kits for determining the thermodynamic stability of nucleic acid duplexes and single polynucleotide polymorphisms via competitive equilibria are provided.
REFERENCES:
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5532129 (1996-07-01), Heller
patent: 5616465 (1997-04-01), Lucas et al.
patent: 5972612 (1999-10-01), Malmqvist et al.
patent: 6210896 (2001-04-01), Chan
patent: 6265163 (2001-07-01), Albrecht et al.
patent: 6815163 (2004-11-01), Breslauer et al.
patent: 0 745 690 (1996-04-01), None
patent: WO 98/18965 (1998-07-01), None
Tinoco, Jr. et al., “Principles and Applications in Biological Sciences”, Physical Chemistry, pp. 451-453, (1978).
Breslauer et al., “Predicting DNA duplex stabilitly from the vase sequence”, Proc. Natl. Acad. Sci., vol. 83, pp. 3746-3750 (1986).
Gelfand et al., “A quantitative method for evaluating the stabilities of nucleic acid”,Proc. Natl. Acad. Sci. USA1999 96:6113-6118.
Holbrook et al., “Enthalpy and heat capacity changes for formation of an Oligomeric DNA Duplex: Interpretation in terms of coupled processes of fomation and association of single-stranded Helices”,Biochemistry1999 38:8409-8422.
Olivas et al., “Competitive triplex/quadruplex equilibria involving guanine-rich oligonucleotides”,Biochemistry1995 34:274-284.
Morrison et al., “Solution-Phase Detection of Polynucleotides Using Interacting Fluorescent Labels and Competitive Hybridization”, 1989 Analytical Biochemistry 183:231-244.
Breslauer Kenneth J.
Gelfand Craig A.
Plum Eric G.
Dann Dorfman Herrell and Skillman
Horlick Kenneth R.
Netter, Jr. Robert C.
Rigaut Kathleen D.
Rutgers The State University of New Jersey
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