Methods and kits for obtaining and analyzing skin samples...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

06949338

ABSTRACT:
Disclosed is a method for removing polynucleotide from the skin. This polynucleotide can be used to detect dermatitis and distinguish an irritant reaction from an allergic reaction by characterizing the polynucleotide according to the polypeptide which it encodes. Additionally, provided are methods for non-invasive isolation of samples from the skin as well as kits for use in the methods provided herein.

REFERENCES:
patent: 4537776 (1985-08-01), Cooper
patent: 4971800 (1990-11-01), Chess et al.
patent: 5460939 (1995-10-01), Hansbrough et al.
patent: 5753612 (1998-05-01), Mitrani
patent: 5811239 (1998-09-01), Frayne
patent: 6054277 (2000-04-01), Furcht et al.
patent: 6056859 (2000-05-01), Ramsey et al.
L. Garofano et al., “PCR based analysis of epidermal cells found on adhesive tape”, Adv. Forensic Haemogenet. 1996, 6:281-283.
K. Paludan et al., “Use of the polymerase chan reaction in quantification of interleukin 8 mRNA in minute epidermal samples”, J. Invest. Derm. 99:830-835, 1992.
Kondo et al. Characterization of Epidermal Cytokine Profiles in Sensitization and elicitaion Phases of Allergic Contact dermatitis as well as Irritant Contact dermatitis in Mouse skin. Lymphokine and Cytokine Res. 1994, vol. 13, No. 6, pp. 367-375.
Nickoloff et al. Keratinocyte Interleukin-10 Expression is Upregulated in Tape-stripped skin, poison ivy dermatitis, and Sezary syndrome, but not in psoriatic plaques. Clinical Immunology and Immunopthology. Oct. 1994, vol. 73, No. 1, pp. 63-68.
Bunge, A. and Guy, R., “Improvement of Methodology for Assessing Bioequivalence of Topical Products,” http://wwwfda.gov/ohrms/dockets/ac/03/slides/3996S2 07 Bunge.pdf. Oct. 22, 2003.
“Draft Guidance for Industry on Topical Dermatological Drug Product NDA's and ANDA's-In Vivo Bioavailability, Bioequivalence, in Vitro Release and Associated Studies: Dermatopharmacokinetieds (DPK) Method Issues”, http://srpub.phrma.org/letters/08.17.98.topical.derm.html. PRMA 1998.
“Washington Report: Skin Tape Stripping Method for Generic Dermatologic Drug Approval Remains in Question”, http://www.aadassociation.org/old/washReports/dec99_washrep.html. 1999.
Rougier et al, “In Vivo Correlation Between Stratum Corneum Reservoir Function and Percutaneous Absorption,”J. Investigative Dermatology,81:275-278 (1983).
Rougier et al, “In Vivo Percutaneous Penetration of Some organic Compounds Related to Anatomic Site in Humans: Predictive Assessment by the Stripping Method,”J. Pharmaceutical Sciences,76:451-454 (1987).
Brand et al., “IL-1β Protein in Human Skin Lymph Does Not Discriminate Allergic from Irritant Contact Dermatitis,”Contact Dermatitis,35:152-156, Munksgaard, Denmark (1996).
Graham, James H., “Basic Pathologic Changes in Skin,” in “Dermal Pathology,” Wd. J H Graham, W C Johnson, and E B Helwig, Harper-Row, Hagerstown, MD, pp. 119-135 (1972).
Grängsjö et al., “Different Pathways in Irritant Contact Eczema? Early Differences in the Epidermal Elemental Content and Expression of Cytokines after Application of 2 Different Irritants,”Contact Dermatitis,35:355-360, Munksgaard, Denmark (1996).
Hoefakker et al., “In vivo Cytokine Profiles in Allergic and Irritant Contact Dermatitis,”Contact Dermatitis,33:258-266, Munksgaard, Denmark (1995).
Holleran et al, “Regulationof epidermal sphingolipid synthesis by permeability barrier function,”J. Lipid Research,32:1151-58 (1991).
Torre and Gino, “Epidermal Cells on Stubs Used for Detection of GSR with SEM-EDX: Analysis of DNA Polymorphisms,”Journal of Forensic Sciences,JFSCA, vol. 41, No. 4, Jul. 1996, pp. 658-659.
Garofano, L. et al., “Comparison of Powerplex® 16 System and Other Multiplex STR Typing Kits on Casework,” (Reporto Carabinieri Investigazioni Scientifiche, Parma, Italia.), 2000 Reference available at: http://www.promega.com/geneticidproc/ussymp11proc/default.htm.
Werfel et al., “Cytokines as Mediators of Allergic Tissue Response,”Allergelogie, Dustri Verlag, Muenchen-Deisenhofen, DE,vol. 20, No. 11, 1997, pp. 546-550.
Werfel, T. et al., “High IL-4 Secretion From Skin-Derived Nickel Specific T-lymphocytes is Associated With Atopy and Acute Eczema Are Associated with in Allergic Contact Dermatitis,”Journal of Allergy and Clinical Immunology,vol. 101, No. 1, Part 2, Jan. 1998 (Jan. 1998), p. S129.
Rowe, A. et al., “Interleukin-4 and the Interleukin-4 Receptor in Allergic Contact Dermatitis,”Contact Dermatitis,vol. 38, No. 1, Jan. 1998 (Jan. 1998), pp. 36-39.
Grangsjo, A. et al., “Different Pathways in Irritant Contact Eczema? Early Differences in the Epidermal Elemental Content and Expression of Cytokines After Application of 2 Different Irritants,”Contact Dermatitis,vol. 35, No. 6, 1996, pp. 355-360.
Howie, Sarah E.M. et al., “Epidermal Keratinocyte Production of Interferon-gama Immunoreactive Protein and mRNA is an Early Event in Allergic Contact Dermatitis,”Journal of Investigative Dermatology,vol. 106, No. 6, 1996, pp. 1218-1223.
Brand, Cu and Braathen, L.R., “Untersuchung Menschlicher Hautlymphe: Unterscheiden Sich Irritative Und Allergische Kontaktdermatititiden Bezüglich ihres Zytokinmusters?, ”Zietschrift Für Hautkrankheiten, vol. 72, 1997, pp. 435-440 Summary Only.
Koning, H. et al., “T Cell Subsets and Cytokines in Allergic and Non-allergic Children. I. Analysis of IL-4, IFN-gamma and IL-13 mRNA Expression and Protein Production,”Cytokine,vol. 9, No. 6, 1997, pp. 416-426.
Corsini and Galli, “Cytokines and Irritant Contact Dermatitis,”Toxicology Letters,vol. 102-103, 1998, pp. 277-282.
Freedberg, Irwin et al., “Keratins and the Keratinocyte Activation Cycle,”The Journal of Investigative Dermatology,vol. 116, No. 5, May 2001, pp. 633-640.
Hamid, Qutayba et al., “In Vivo Expression of IL-12 and IL-13 In Atopic Dermatitis,”Journal of Allergy and Clinical Immunology,vol. 98, No. 1, Jul. 1996, pp. 1-8.
Junghans, Volker et al., “Epidermal Cytokines IL-1β, TNF-α, and IL-12 in Patients with Atopic Dermatitis: Response to Application of House Dust Mite Antigens,”The Journal of Investigative Dermatology,vol. 111, No. 6, Dec. 1998, pp. 1184-1188.
Ohmen, Jeffrey D. et al., “Overexpression of IL-10 in Atopic Dermatitis,”The Journal of Immunology,vol. 154, 1995, pp. 1956-1963.
Ryan and Gerberick, “Cytokine mRNA Expression in Human Epidermis After Patch Treatment With Rhus and Sodium Lauryl Sulfate,”American Journeal of Contact Dermatitis,vol. 10, No. 3, Sep. 1999, pp. 127-135.
Yawalkar and Pichler, “Pathogenesis of Drug-Induced Exanthema,” Int Arch Allergy Immunol, vol. 124, 2001. pp. 336-338.
Farage, M.A., et al., “Development of a Noninvasive Method for Assessing Human Skin Irritation,” The Toxicologist (1997) vol. 36, No. 1, Part. 2, pp. 365.
Nickoloff, B.J., M.D., Ph.D., et al., “Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin,” Journal of the American Academy of Dermatology (1994) vol. 30, No. 4, pp. 535-546.
Tetsuji, H., et al., “Elevation of Interleukin 1 Receptor Antagonist in the Stratum Corneum of Sun-exposed and Ultraviolet B-irradiated Human Skin,” The Journal of Investigative Dermatology (1996) vol. 106, No. 5, pp. 1102-1107.
Weigand, D.A., M.D., et al., “Removal of Stratum Corneum in Vivo: An Improvement on the Cellophane Tape Stripping Technique,” The Journal of Investigative Dermatology (1973) vol. 60, No. 2, pp. 84-87.
Van Hoogdalem, Ewoud J., “Assay of Erythromycin in Tape Strips of Human Stratum corneum and Some Preliminary Results in Man” Skin Pharmacol (1992) vol. 5, pp. 124-128.
van der Molen. R.G., et al., “Tape stripping of human stratum corneum yields cell layers that originate from various

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and kits for obtaining and analyzing skin samples... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and kits for obtaining and analyzing skin samples..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and kits for obtaining and analyzing skin samples... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3386479

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.