Methods and kits for detection of thromboxane A2 metabolites

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007910, C435S007920

Reexamination Certificate

active

07727730

ABSTRACT:
Methods, compositions and kits are provided for measuring aspirin's anti-thrombotic effectiveness on a subject. Included are a novel assay for quickly and specifically measuring TxA2 metabolite levels in urine and correlating the levels with aspirin dose in a subject. The methods, compositions and kits utilize a novel anti TxA2 metabolite antibody.

REFERENCES:
patent: 5047354 (1991-09-01), Foegh et al.
patent: 6589756 (2003-07-01), Barlow
patent: 6967083 (2005-11-01), Ens
Chiabrando et al. Anal. Biochem. 1987 vol. 163, p. 255-262.
Chiabrando et al. (Anal. Biochem 1987, vol. 163, p. 255-262).
Campbell “General properties and applications of monoclonal antibodies” 1984 Elsevier Science Publisher, Section 1.1 to Section 1.3.4, p. 1-29).
Tsuruta et al. Prostaglandins, Leukotrienes and Essential Fatty Acids 2003 vol. 68, p. 273-284.
Antithrombotic Trialists' Collaboration, BMJ, 324:71-86, 2002.
Lopez et al., Nat. Med., 4:1241-1243, 1998.
Awtry et al., Circulation, 101:1206-1218, 2000.
Hamberg et al., PNAS, 72:2994-2998, 1975.
Ellis et al., Science, 193:1135-1137, 1976.
Bhatt et al., Nature Rev., 2:15-28, 2003.
Hankey et al., Lancet, 367:606-617, year 2000.
Gum et al., Am J Cardiol, 88:230-235, 2001.
Tarjan et al., Orv. Hetil, 140:2339-2343, 1999, English Abstract Only.
Sane et al., Am J Cardiol, 90:893-895, 2002.
Helgason et al., Stroke, 25:2331-2336, 1994.
Hosoda, H, et al., Chem. Pharm. Bull. 29:1969-1974, 1981.
Goding, J.W., J. Immunol. Methods 39:285-308, 1980.
Hayashi Y., et al., Anal. Biochem. 187: 151-159, 1990.

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