Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-08-03
1979-09-04
Berch, Mark L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260326N, 548230, C07D20508, C07D40304
Patent
active
041668162
ABSTRACT:
The stereospecific cycloaddition of nitrogen containing acetic acid halides or anhydrides with Schiff bases having a carbalkoxy group substituted on the methine carbon atom offers new intermediates and methods for preparing synthetic cephalosporin congeners having antibacterial activity.
REFERENCES:
patent: 3943123 (1976-03-01), Bose
Mukerjee et al., Synthesis, (1973), pp. 334-337.
Weissberger, Heterocyclic Compounds, vol. 19, pt. 2, pp. 937-939 (1964).
Bose et al. I, Tet. Letters 1973, 2319-2320.
Bose et al. II, Chem. Abs. 79, 31750e, (1973).
Gleason John G.
Holden Kenneth G.
Huffman William F.
Berch Mark L.
Edgerton William H.
SmithKline Corporation
Williams Janice E.
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