Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1989-08-28
1992-11-10
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514740, 514399, 564511, A01N 3744
Patent
active
051623730
ABSTRACT:
Disclosed are total parenteral nutrition formulations which include essential amino acids in combination with either arginine or ornithine, for use in detection of recurrent malignant disease in patients. Such formulations stimulate tumor-specific polyamine production to a greater extent than non-tumor related polyamine production. Additionally, such formulations were found to specifically promote an increase in red block cell putrescine levels of tumor-bearing rats. Nontumor-bearing rats were not found to be similarly reactive to these formulations. Methods for making and administering these formulations as well as their use in preventing DFMO-induced toxicity are also disclosed.
The present invention also comprises formulations for use in the rejuvinati o
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Ajani Jaffer
Grossie, Jr. Bruce
Nishioka Kenji
Ota David M.
Board of Regents , The University of Texas System
Carr Deborah D.
Dees Jos,e G.
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