Methods and devices for measuring tear film and diagnosing...

Optics: eye examining – vision testing and correcting – Eye examining or testing instrument – Methods of use

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C351S221000

Reexamination Certificate

active

07959293

ABSTRACT:
Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release.

REFERENCES:
patent: 6236459 (2001-05-01), Negahdaripour et al.
patent: 7281801 (2007-10-01), Wang
patent: 7758190 (2010-07-01), Korb et al.
patent: 2004/0212781 (2004-10-01), Mihashi et al.
patent: 2006/0109423 (2006-05-01), Wang
Fogt N., et al., “Interferometric Measurement of Tear Film Thickness By Use of Spectral Oscillations,” Journal of Optical Society of America, 1998, vol. 15 (1), pp. 268-275.
Gardner et al., “Tear Film Thickness: Responsiveness to Potential Cognitive Demands,” American Academy of Optometry, Tampa Dec. 2004, 1 page.
Geldis et al., “The Impact of Punctual Occulsion on Soft Contact Lends Wearing Comfort and the Tear Film,” Eye and Contact Lens, pp. 261-265, 2008, vol 34 (5).
Hinel E., et al., Concurrent interferometric Measures of Lipid Layer Thickness and Tear Film Thinning Before and After Application of Lipid Emulsion Drop, American Academy of Optometry, Anaheim Oct. 2008, 1 page.
International Search Report for Application No. PCT/US08/062682, mailed on Nov. 5, 2008, 6 pages.
K1ng-Smith P. E. et al., “Interferometric imaging of the full thickness of the precorneal tear film,” Journal of the Optical Society of America A (Optics, Image Science and Vision), pp. 2097-2104, 2006, vol. 23 (9), Opt. Soc. America USA.
Kimball et al., “Evaporation is the Primary Mechanism of Pre-Corneal Tear Film Thinning”, American Academy of Optometry, Anaheim Oct. 22, 2008, 1 page.
Kimball et al., Improving Interferometric Tear Thickness Measurements by Using Longer Wavelengths. American Academy of Optometry, Denver Dec. 2006, 1 page.
King S., et al., “Three Interferometric Methods For Measuring The Thickness Of Layers Of The Tear Film,” Optometry and Vision Science, 1999, vol. 76 (1), pp. 19-32.
King-Smith., et al., “Why does Dry Eye Affect Inferior Cornea More than Superior Cornea?,” American Academy of Optometry, Dec. 15, 2002, pp. 1-2.
King-Smith et al., “In vivo Measurement of the Thickness of Human Corneal Endothelium and Descemets Membrane Using Interferometry, E-Abstract 157,” Investigative Ophthalmology & Visual Science, 2002, vol. 43.
King-Smith et al., “Measurement of the Thickness of the Lipid Layer of the Tear Film Using Reflection Spectra,Grand Floridian A, Program 1540,” Association for Research in Vision and Ophthalmology, Apr. 2008, 1 page.
King-Smith et al., “Roughness of the Corneal Surface by Interferometry”, Association for Research in Vision and Ophthalmology, May 6, 2007, 1 page.
King-Smith et al., “The Thickness of the Human Precorneal Tear Film: Evidence from Reflection Spectra,” Investigative & Visual Science, pp. 3348-3359, 2000, vol. 41 (11).
King-Smith et al., “The Thickness of the Tear Film,” Current Eye Research, pp. 357-368, 2004, vol. 29 (4-5), Taylor & Francis Health Sciences.
King-Smith P., et al., “Interferometric Analysis of Reflections from the Tear Film and Ocular Surface”. American Academy of Optometry, 2003, 1 page.
King-Smith P.E., et al., “A Tear Layer of Thickness 1.6 to 7.3 Micrometer Determined from Reflectance Spectra,” Investigative Ophthalmology & Visual Science, 1998, vol. 39 (4), pp. 2446-B303.
King-Smith P.E., et al., “Can the Mucus Layer of the Tear Film be Deomstrated by Interferometry?,” Investigative Ophthalmology & Visual Science, 2004, vol. 45, pp. 1-2.
King-Smith P.E., et al., “Further Evidence that the Thickness of the Normal Human Tear Film is about 3 Micrometre,” Investigative Ophthalmology & Visual Science, 2000, vol. 41 (4), pp. 337-B337.
King-Smith P.E., et al., “Is the Thickness of the Tear Film About 40 Micrometre or About 3 Micrometre?,” Investigative Ophthalmology & Visual Science, 1999, vol. 40 (4), pp. 2876-B751.
King-Smith P.E., et al., “Measurement of Tear Film Thickness by Spectro-Photometry,” Investigative Ophthalmology & Visual Science, 1996, vol. 37 (3), pp. 4984-B594.
King-Smith P.,et al., “Is Inferior Tear Film Thinner than Superior Tear Film?,” Investigative Ophthalmology & Visual Science, 2003, vol. 44, p. 2476.
Korb D. R. et al., “The effect of two novel lubricant eye drops on tear film lipid layer thickness in subjects with eye symptoms,XP009103830,” Opometry and Vision Science, Williams and Wilkins, pp. 594-601, 2005, vol. 82 (7), Baltimore, MD, US.
Nichols, et al., “Assessing Visual Parameters in Dry Eye Disease,” American Academy of Optometry, Anaheim Oct. 22, 2008, 1 page.
Nichols et al., “Lipid Layer Thickness and Tear Film Thinning Before and After Application of a Lipid Emulsion,, Drop” Association for Research in Vision and Ophthalmoogy, 2008, 1 page.
Nichols et al., “Tear Film Thickness and Thinning Rate Following a Six-Week Trial of 2% Diquafosol Tetrasodium vs. Placebo in Dry Eye Patients,” Association for Research in Vision and Ophthalmology, Apr. 30, 2006, pp. 1-2.
Nichols et al., “The Impact of Contact Lens Care Solutions on the Thickness of the Tear Film and Contact Lens,” Cornea, Clinical Sciences, pp. 825-832, 2005, vol. 24 (7).
Nichols J.J., et al., “Hydrogel Contact Lens Binding Induced by Contact Lens Rewetting Drops,” Optometry and Vision Science, 2008, vol. 85(4), pp. 236-240.
Nichols J.J., et al., “Thickness of The Pre- and Post-Contact Lens Tear Film Measured In Vivo by Interferometry,” Investigative Ophthalmology & Visual Science, 2003, vol. 44 (1), pp. 68-77.
Nichols J.J., et al., “Thinning Rate of the Precorneal and Prelens Tear Films,” Investigative Ophthalmology & Visual Science, 2005, vol. 46 (7), pp. 2353-2361.
Nicols et al, “Role of Lipid Layer as a Barrier to Pre-Lens Tear Film Thinning,” American Academy of Optometry, Anaheim Oct. 25, 2008, 1 page.
King-Smith. et al., “Noninvasive Measurement of the Thickness of the Human Corneal Endothelium and Descemet's Membrane”, American Academy of Optometry, Dec. 8, 2001, pp. 1-2.
Schlote T., et al., “Marked reduction and distinct patterns of eye blinking in patients with moderately dry eyes during video display terminal use,” Graefe's Archive for Clinical and Experimental Ophthalmology, 2004, vol. 242 (4), pp. 306-312.
Yap M, “Tear break-up time is related to blink frequency ,XP009107174,” ACTA Ophthalmologica , pp. 92-94, 1991, vol. 69 (1).
Zhu Heng et al ., “A mathematical model for ocular tear and solute balance,XP002500490,ISSN: 0271-3683,” Current Eye Research Oct. 2005, pp. 841-854, 2005, vol. 30 (10).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and devices for measuring tear film and diagnosing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and devices for measuring tear film and diagnosing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and devices for measuring tear film and diagnosing... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2632520

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.