Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Reexamination Certificate
2008-09-02
2010-02-23
Fortuna, Ana M (Department: 1797)
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
C204S600000, C204S627000, C210S321750
Reexamination Certificate
active
07666289
ABSTRACT:
Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from passing, or inhibited, on application of an appropriate electric field waveform. The pores of the substrate produce nonuniform electric field having local extrema located near the pores. These nonuniform fields drive dielectrophoresis, which produces the inhibition. Arrangements of electrodes and porous substrates support continuous, bulk, multi-dimensional, and staged selective concentration.
REFERENCES:
patent: 3706614 (1972-12-01), Kirkpatrick
patent: 5403455 (1995-04-01), Candor
patent: 5560811 (1996-10-01), Briggs et al.
patent: 5858192 (1999-01-01), Becker
patent: 5979670 (1999-11-01), Ditter
patent: 6267898 (2001-07-01), Fukuda
patent: 6648147 (2003-11-01), Lydon
patent: 6780584 (2004-08-01), Edman
patent: 6905029 (2005-06-01), Flagan
patent: 7198702 (2007-04-01), Washizu et al.
patent: 7537809 (2009-05-01), Ochiai et al.
M. P. Hughes; H. Morgan; F. J. Rixon; J. P.H. Burt; R. Pethig; “Manipulation of herpes simplex virus type 1 by dielectrophoresis”, Biochimica et Biophysica Acta 1425, 1998, pp. 119-126.
H. A. Pohl; “The Motion and Precipitation of Suspensoids in Divergent Electric Fields”, Journal of Applied Physics, 1951, vol. 22, No. 7, pp. 869-871.
Y. Huang; X-B. Wang; F. F. Becker; P. R.C. Gascoyne; “Introducing Dielectrophoresis as a New Force Field for Field-Flow Fractionation”, Biophysical Journal, 1997, vol. 73, pp. 1118-1129.
J. Yang; Y. Huang; X-B. Wang; F. F. Becker; P. R.C. Gascoyne; “Cell Separation on Microfabricated Electrodes Using Dielectrophoretic/Gravitational Field-Flow Fractionation”, Analytical Chemistry, 1999, vol. 71, pp. 911-918.
E. B. Cummings; A. K. Singh; “Dielectrophoresis in Microchips Containing Arrays of Insulating Posts: Theoretical and Experimental Results”, Analytical Chemistry, 2003, vol. 75, pp. 4724-4731.
B. H. Lapizco-Encinas; B. A. Simmons; E. B. Cummings; Y. Fintschenko; “Insulator-based dielectrophoresis for the selective concentration and separation of live bacteria in water”, Electrophoresis 2004, vol. 25, pp. 1695-1704.
B. H. Lapizco-Encinas; B. A. Simmons; E. B. Cummings; Y. Fintschenko; “Dielectrophoretic Concentration and Separation of Live and Dead Bacteria in an Array of Insulators”, Analytical Chemistry, 2004, vol. 76, pp. 1571-1579.
Cummings Eric B.
Fiechtner Gregory J.
Fintschenko Yolanda
McGraw Gregory J.
Salmi Allen
Evans Timothy P.
Fortuna Ana M
Sandia Corporation
Smith , Gambrell & Russell, LLP
LandOfFree
Methods and devices for high-throughput dielectrophoretic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and devices for high-throughput dielectrophoretic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and devices for high-throughput dielectrophoretic... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4152783