Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-04-14
2010-02-09
Richter, Johann R (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S561000, C514S859000, C514S863000, C540S145000, C562S567000, C424S009610, C600S002000, C607S001000
Reexamination Certificate
active
07659301
ABSTRACT:
Methods for preventing damage to the epidermis during PDT induced using a pre-photosensitizing agent are provided. The methods of the present invention utilize spatial confinement to control formation of a photoactive species from a topically-applied pre-photosensitizing agent. In one embodiment, thermal inhibition is used to prevent the metabolism of a pre-photosensitizing agent in epithelial tissue surrounding a treatment site. In another embodiment, a chemical inhibitor can be applied to the epithelial tissue to inhibit the conversion of a pre-photosensitizing agent into a phototoxic species.
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Anderson Richard Rox
Joe Edwin K.
Ortel Bernhard
Karpinski Luke E
Nutter & McClennen & Fish LLP
Richter Johann R
The General Hospital Corporation
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