Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-05-12
1999-07-06
Brouillette, D. Gabrielle
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424426, 424443, 424444, 606228, 606229, 606230, A61F 1300
Patent
active
059194731
ABSTRACT:
An analgesic agent delivery system and method of treating postoperative pain comprising an analgesic agent such as morphine and an extended-release drug delivery device. The device may be placed in the vicinity of a wound and then provide an extended-release of the analgesic agent over a period of time, thereby controlling the pain emanating from the wound.
REFERENCES:
patent: 3275510 (1966-09-01), Magid et al.
patent: 3728839 (1973-04-01), Glick
patent: 3849185 (1974-11-01), Shepherd et al.
patent: 3991766 (1976-11-01), Schmitt et al.
patent: 4024871 (1977-05-01), Stephenson
patent: 4175326 (1979-11-01), Goodson
patent: 4373217 (1983-02-01), Draenert
patent: 4416886 (1983-11-01), Bernstein
patent: 4450150 (1984-05-01), Sidman
patent: 4464378 (1984-08-01), Hussain
patent: 4493848 (1985-01-01), Lehann et al.
patent: 4582052 (1986-04-01), Dunn et al.
patent: 4626539 (1986-12-01), Aungst et al.
patent: 4708870 (1987-11-01), Pardini
patent: 4764377 (1988-08-01), Goodson
patent: 4806341 (1989-02-01), Chien
patent: 4871750 (1989-10-01), Roberts
patent: 4897260 (1990-01-01), Ross et al.
patent: 5019096 (1991-05-01), Fox et al.
patent: 5069909 (1991-12-01), Sharma
patent: 5149538 (1992-09-01), Granger
patent: 5226912 (1993-07-01), Kaplan et al.
patent: 5240711 (1993-08-01), Hille
patent: 5282829 (1994-02-01), Hermes
patent: 5366081 (1994-11-01), Kaplan et al.
patent: 5458582 (1995-10-01), Nakao
patent: 5589480 (1996-12-01), Elkhoury et al.
patent: 5660854 (1997-08-01), Hayes
Lesser, G. J., et al, Pain, in vitro and in vivo studies of subcutaneous hydromorphone implants designed for the treatmentof cancer pain, vol. 65, (1996), pp. 265-272.
"Intra-articular morphine for pain relief after knee arthroscopy," G.P. Joshi et al. The Journal of Bone and Joint Surgery, vol. 74-B, No. 5, Sep. 1992, pp. 749-751.
English Language Abstract of WO 9213540-A1, dated Feb. 6, 1991.
Back et al. "Analgesic Effect of Topical Opioids on Painful Skin Ulcers," in Journal of Pain and Symptom Management, vol. 10, No. 7, Oct. 1995.
Basbaum et al., "Opiate Analgesia,"N. Engl. J. Med., 325:1168-1169, 1991.
Dickenson, "Neurophysiology of Opioid Poorly Responsive Pain," Cancer Surveys vol. 21: Palliative Medicine: Problem Areas in Pain and Symptom Management, 1994, pp. 5-16.
Gates and Holloway, "A Comparison of Wound Environments,"Ostomy/Wound Management, Oct. 1992, vol. 38 No. 8.
Giardina et al., "Central and Peripheral Analgesic Agents: Chemical Strategies for Limited Brain Penetration in Kappa-Opioid Agonists Belonging to Different Chemical Classes," Il Farmaco, 50(6),405-418 (1995), pp. 405-418.
Herz, "Role of Immune Processes in Peripheral Opioid Analgesia," in The Brain Immune Axis and Substance Abuse, Plenum Press, New York, 1995, pp. 193-199.
Joris et al., "Opioid Analgesia at Peripheral Sites" Anesth, Analg. 66:1277-81, International Anesthesia Research Soc., 1987.
Jaffe and Martin, "Opioid Analgesics and Antagonists" in Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th Edition (1990).
Khoury et al., "Intraarticular Morphine, Bupivacaine, and Morphine/Bupivacaine for Pain Control After Knee Videoarthroscopy," Anesthes. 77:263-266 (1992).
Kinnman et al., "Peripherally Administrated Morphine Attenuates Capsaicin-Induced Mechanical Hypersensitivity in Humans," Anesth Analg, 1997, 84:595-599.
Makman, "Morphine receptors in immunocytes andneurons," Advances in Neuroimmunology, vol. 4, pp. 69-82, 1994.
Mather, "Opioids: A Pharmacologist's Delight|" Australasian Society of Clincal and Experimental Pharmacologists and Toxicologists Symposium, 1994, Clinical and Experimental Pharmacology and Physiology (1995) 22, 833-836.
Needham, "Painless Lumbar Surgery: Morphine Nerve Paste," Connecticut Medicine, vol. 60, No. 3, Mar. 1996, pp. 141-143.
Peyman et al., "Effects of morphine on corneal sensitivity and epithelial wound healing: implications for topical ophthalmic analgesia,"LSU Eye Center, Louisiana State University Medical Center School of Medicine, Accepted for publication Aug. 26, 1993.
Regan, "The Use of Intrasite Gel in Healing Open Sternal Wounds,": Ostomy/Wound Management, Apr. 1992, vol. 38 No. 3, pp. 15-21.
Reisine and Pasternak, "Opioid Analgesics and Antagonists," in Goodman and Gilman's The Pharmacological Basis of Therapeutics, Ninth Edition, Chapter 23, pp. 521-544, 1996.
Schwartz and Wiseman, "Surgical Supplies," Chapter 108, pp. 1873-1882, 1990.
Siddall et al., "Pain Mechanisms and Management: An Update," Clinical Experimental Pharmacology and Physiology (1995) 22, 679-688.
Stein et al., "Antinociceptive effects of mu-and kappa-agonists in inflammation are enhanced by a peripheral opioid receptor-specific mechanism of action," Eur. J. Pharmacol. 155:255-264 (1988).
Stein, "The Control of Pain in Peripheral Tissue by Opioids," Mechanisms of Disease, Jun. 22, 1995, vol. 332, No. 25, pp. 1685-1690.
Stein et al., "No Tolerance to Peripheral Morphine Analgesia in Presence of Opioid Expression in Inflamed Synovia," J. Clin. Invest., vol. 98, No. 3 Aug. 1996, 793-799.
Stein et al., "Opioids as novel intro-articular agents in arthritis," in Progress in Pain Research and Management, Fields, H.L., and Liebeskind, J.C., eds., 1:289-296, IASP Press, Seattle (1994).
Stein et al., "Peripheral and non-neuronal opioid gffects," Curr. Opin. Anasth. 7:347-351 (1994).
Stein et al., "Peripheral effect of fentanyl upon noiception in inflamed tissue of the rat," Neurosci. Lett. 84:225-228 (1988).
Stein, "Peripheral Mechanisms of Opioids Analgesia" Anesth. Analg. (1993), pp. 182-191.
Stein et al., "Peripheral Opioid Receptors," Annals of Medicine 27:219-221, 1995.
Stein et al., "Analgsic Effect of Intracellular Morphine After Arthroscopic Knee Surgery," N. Engl. J. Med.,325:1123-1126 (1991).
Tennant et al., "Topical Morphine for Peripheral Pain" in the Letters to the Editor in The Lancet vol. 342 (1993) pp. 1047-1048.
Thomas, "In Vitro Investigations of a New Hydrogel Dressing," Journal of Wound Care, Mar. 1996, vol. 5 No. 3, pp. 130-131.
Thompson and Pierce, "Local Analgesia with Opioid Drugs," The Annals of Pharmacotherapy, Feb. 1995, vol. 29, pp. 189-190.
Traynor, "Opioid Receptors and Their Subtypes: Focus on Peripheral Isolated Tissue Preparations,"Neurochem, Int., vol. 24, No. 5, pp. 427-432, 1994.
Williams, "Intrasite Gel: a hydrogel dressing, 1994".
"DepoMorphine Investigational New Drug Application Filed," Press Release from DepoTech Corp., Dec. 9, 1996, http://www.pslgroup.com/dg/eafa.htm.
"Under Skin Pain Implant Developed," Press Release from Johns Hopkins Medical Institutions, Jul. 25, 1996, http://www.ari.net
ewswise/articles/PAINPOL.JHM.html.
LandOfFree
Methods and devices for delivering opioid analgesics to wounds v does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and devices for delivering opioid analgesics to wounds v, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and devices for delivering opioid analgesics to wounds v will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-897372