Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Reexamination Certificate
2002-05-01
2010-06-29
Alexander, Lyle A (Department: 1797)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
C422S082010, C422S082110, C436S149000
Reexamination Certificate
active
07744816
ABSTRACT:
The methods and apparatus100, disclosed herein are of use for sequencing150and/or identifying160proteins230, 310, polypeptides230, 310or peptides230, 310. Proteins230, 310containing labeled amino acid residues may be synthesized and passed through nanopores255, 330. A detector257, 345operably coupled to a nanopore255, 330may detect labeled amino acid residues as they pass through the nanopore255, 330. Distance maps140for each type of labeled amino acid residue may be compiled. The distance maps140may be used to sequence150and/or identify160the protein230, 310. In different embodiments of the invention, amino acid residues labeled with luminescent labels235, 245or nanoparticles315may be detected using photodetectors257or electrical detectors345. Apparatus100of use for protein230, 310sequencing150and/or identification160are also disclosed herein.
REFERENCES:
patent: 4962037 (1990-10-01), Jett et al.
patent: 5306403 (1994-04-01), Vo-Dinh
patent: 5324637 (1994-06-01), Thompson et al.
patent: 5332666 (1994-07-01), Prober et al.
patent: 5405747 (1995-04-01), Jett et al.
patent: 5436130 (1995-07-01), Mathies et al.
patent: 5721102 (1998-02-01), Vo-Dinh
patent: 5776674 (1998-07-01), Ulmer
patent: 5783389 (1998-07-01), Vo-Dinh
patent: 5814516 (1998-09-01), Vo-Dinh
patent: 5821058 (1998-10-01), Smith et al.
patent: 5866336 (1999-02-01), Nazarenko et al.
patent: 6002471 (1999-12-01), Quake
patent: 6146227 (2000-11-01), Mancevski
patent: 6174677 (2001-01-01), Vo-Dinh
patent: 6210896 (2001-04-01), Chan
patent: 6355420 (2002-03-01), Chan
patent: 2003/0059822 (2003-03-01), Chan et al.
patent: 99/50654 (1999-10-01), None
patent: 0125794 (2001-04-01), None
patent: 03078649 (2003-09-01), None
patent: 03106620 (2003-12-01), None
Lillo, et al., 1997. “Design and Characterization of a Multisite Fluorescence Energy-Transfer System for Protein Folding Studies: A Steady-State and Time-Resolved Study of Yeast Phoshpglycerate Kinase”. Biochemistry 36: 11261-11272.
Fisher, et al., 1999. “Lipid Induced Conformational Changes in the N-Terminal Domain of Human Apolipoprotein E”. Journal of Lipid Research 40: 93-99.
Berlin Andrew A.
Su Xing
Alexander Lyle A
Intel Corporation
Pillsbury Winthrop Shaw & Pittman LLP
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