Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-03-08
2005-03-08
Tate, Christopher R. (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S002600
Reexamination Certificate
active
06864239
ABSTRACT:
A GPCR-like protein is described, as well as inhibitory/antagonistic compounds and compositions comprising such inhibitors/antagonists of the protein. Such compounds may be used for treating elevated intraocular pressure and conditions associated with elevated intraocular pressure, such as glaucoma.
REFERENCES:
Dong et al., (2001) “A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons”,Cell, 106:619-632.
Gonzalez et al., (2000) “Characterization of Gene Expression in Human Trabecular Meshwork Using Single-Pass Sequencing of 1060 Clones”,Invest. Ophtalmol. Vis. Sci., 41:3678-3693.
(2000) GenBank Accession No. BE439409; HTM1-025F1 Homo Sapiens cDNA, mRNA seqeunce.
Abran Daniel
Moffett Serge
Peri Krishna G.
Darby & Darby
Harle Jennifer Ione
Tate Christopher R.
Theratechnologies Inc.
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