Chemistry: analytical and immunological testing – Optical result
Reexamination Certificate
2005-12-06
2005-12-06
Chin, Chris (Department: 1641)
Chemistry: analytical and immunological testing
Optical result
C435S004000, C435S006120, C435S007100, C435S007900, C435S007920, C435S968000, C436S501000, C436S528000, C436S538000, C436S546000, C436S547000, C436S164000, C436S172000, C436S056000, C436S519000
Reexamination Certificate
active
06972198
ABSTRACT:
The invention relates to a method for determining the conformational state of a protein, comprising the steps of: a) providing a first binding partner which is capable of binding to the protein in a manner dependent on the conformational state of the protein and which generates a signal in a manner dependent on the binding of the first binding partner to the protein; and b) contacting the protein with the first binding partner and determining the conformational state of the protein by assessing the labelling of the protein by the binding of the first binding partner.
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Colyer John
Craig Roger K.
Chin Chris
Cyclacel Ltd.
FitzGerald Mark J.
Gabel Gailene R.
Palmer & Dodge LLP
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