Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...
Patent
1994-03-18
1998-05-19
Loring, Susan A.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds hormone or other secreted growth regulatory factor,...
4241431, 4241451, 4241551, 4241741, 53038824, 5303888, 53038825, 53038822, A61K 39395, A61K 4900, C87K 1628, C07K 1618
Patent
active
057532303
ABSTRACT:
The present invention describes methods for inhibition of angiogenesis in tissues using vitronectin .alpha..sub.v .beta..sub.3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing anti-.alpha..sub.v .beta..sub.3 monoclonal antibodies.
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Brooks Peter
Cheresh David A.
Fitting Thomas
Holmes Emily
Loring Susan A.
The Scripps Research Institute
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