Methods and compositions to prevent formation of adhesions...

Details Methods and compositions to prevent formation of adhesions... Methods and compositions to prevent formation of adhesions...

2006-04-18

2006-04-18

Webman, Edward J. (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S423000, C514S772100, C427S002120, C427S002240, C427S002280

Reexamination Certificate

active

07029688

ABSTRACT:
The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form following surgical procedures, are minimized. These materials contain a polymer of hydrophilic molecules such as polyethylene glycol (PEG) bound to a polymer that spontaneously adsorbs to biological tissue such as phenylboronic acid (PBA). The PEG-PBA co-polymer can be formed in a variety of geometries. The materials can also be used to coat prosthetics and other implants.

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