Methods and compositions to improve germ cell and embryo...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C435S002000

Reexamination Certificate

active

07838509

ABSTRACT:
Sperm, oocyte, and embryo survival and function is improved in vivo or in vitro by the use of a polysaccharide containing arabinose, galactose and/or hexuronic acid. In particular, a nonspermicidal lubricant containing such a polysaccharide (e.g., gum arabic, pectin, or galacturonic acid) increases the fertilization potential of the sperm during coitus, artificial insemination or sperm collection. Similarly, a freezing medium containing a polysaccharide containing arabinose, galactose and/or hexuronic acid enhances sperm, oocyte, or embryo viability.

REFERENCES:
patent: 3393678 (1968-07-01), Picini
patent: 3718740 (1973-02-01), Hafs et al.
patent: 4007087 (1977-02-01), Ericsson
patent: 4039662 (1977-08-01), Hecht et al.
patent: 4804537 (1989-02-01), Bergman et al.
patent: 4804674 (1989-02-01), Curtis-Prior et al.
patent: 4818751 (1989-04-01), Ibe
patent: 5071741 (1991-12-01), Brockbank
patent: 5106615 (1992-04-01), Dikstein
patent: 5116969 (1992-05-01), Adams et al.
patent: 5198217 (1993-03-01), Vedros
patent: 35 16 398 (1985-11-01), None
patent: 380 084 (1990-08-01), None
patent: 608511 (1994-08-01), None
patent: 661 028 (1995-07-01), None
patent: 59-059605 (1984-04-01), None
patent: 5-076332 (1993-03-01), None
patent: 604556 (1978-04-01), None
patent: 685285 (1979-09-01), None
Virno et al. Amer. J. Ophthamol. 1966. 62(5), 824-833.
Cox G. J. Science. Dec. 1937, vol. 86, No. 242, pp. 540-542.
The MERCK Index. 1989. p. 1118.
Amelar et al., “Sperm Motility,”Fertility and Sterility34(3):197-215, Sep. 1980.
Bongso et al., “Improved sperm concentration, motility, and fertilization rates following Ficoll treatment of sperm in a human in vitro fertilization program,”Fertility and Sterility51(5):850-854, 1989.
Boyers et al., “The Effects of Lubrin on Sperm Motility In Vitro,”Fertility and Sterility47(5):882-884, May 1987.
Buchala et al., “Polysaccharides in the culture medium of cotton cells cultured in vitro,”Food Hydrocolloids1(5/6):359-363, 1987.
Frishman et al., “Evaluation of Astroglide, a New Vaginal Lubricant: Effects of Length of Exposure and Concentration on Sperm Motility,”Fertility and Sterility58(3):630-632, Sep. 1992.
G. Maisse, “Comparison of different carbohydrates for the cryopreservation of rainbow trout (Oncorhynchus mykiss) sperm,”CAB International, Abstract No. 940104586, 1994 & see alsoAquatic Living Resources7(3):217-219, 1994.
Garcia et al., “Development of a buffer system for dialysis of . . . ,”Theriogenology31(5), Abstract only, 1989.
Goldenberg and White, “The Effect of Vaginal Lubricants on Sperm Motility In Vitro,”Fertility and Sterility26(9):872-873, Sep. 1975.
Hill et al., “Use of arabinogalactan to obtain washed murine platelets free of contaminating plasma proteins and appropriate for studies of function, morphology, and thrombopoiesis,”The Journal of Laboratory and Clinical Medicine, 61stAnnual Meeting, Nov. 9-11, 1988.
Karow et al., “Effects of Temperature, Potassium Concentration, and Sugar on Human Spermatozoa Motililty: A Cell Preservation Model from Reproductive Medicine,”Cryobiology29:250-254, 1992.
Katsoff et al., “Chymotrypsin-galactose treatment of sperm with antisperm antibodies results in improved pregnancy rates following in vitro fertilization,”American Journal of Reproductive Immunology33:149-154, 1995.
Kutteh et al., “Vaginal Lubricants for the Infertile Couple: Effect on Sperm Activity,”Int. J. Fertil.41(4):400-404, 1996.
Miller et al., “The Effect of a Surgical Lubricant on In Vivo Sperm Penetration of Cervical Mucus,”Fertility and Sterility61(6):1171-1173 , Jun. 1994.
Neuwinger et al., “Hyaluronic acid as a medium for human sperm migration tests,”Human Reproduction6(3):396-400, 1991.
Platov et al., “Freezing ram semen in diluents containing polysaccharides,”CAB InternationalAbstract No. 810160548, 1980.
Tagatz et al., “The Effect of Vaginal Lubricants on Sperm Motility and Viability In Vitro,”Am. J. Obstet. Gynecol.113(1):88-90, 1972.
The Merck Index. Encyclopedia of Chemicals, Drugs and Biologicals. 1989. p. 284,285,705, 1118, 11139.
Tulandi and McInnes, “Vaginal Lubricants: Effect of Glycerin and Egg White on Sperm Motility and Progression In Vitro,”Fertility and Sterility41(1):151-153, Jan. 1984.
Wikland, et al, “A self-migrating method for preparation of sperm for in-vitro fertilization”Human Reprod2(3): Abstract, Apr. 1987.

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