Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing
Reexamination Certificate
2004-05-07
2008-10-21
Lilling, Herbert J. (Department: 1657)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
C424S439000, C977S775000, C977S801000
Reexamination Certificate
active
07438903
ABSTRACT:
Bioavailability of Coenzyme-Q10 (“Co-Q10”), an oil-soluble substance, can be enhanced in a subject by modifying, e.g. nanonizing or charging, the form of Co-Q10. Co-Q10 bioavailability also can be enhanced by administering Co-Q10 to the subject as an oil (lipid)-based and water (hydro)-based mixed composition, along with other optional components, such as oils, resins and other carriers. Accordingly, the invention provides various Co-Q10 compositions, e.g. compositions comprised of (i) Co-Q10 dissolved in one or more Co-Q10-soluble oils and (ii) Co-Q10 in admixture with at least one water-dispersible agent. A Co-Q10 complex of the invention, therefore, yields an increased cell absorption rate, as well as an enhanced percentage of Co-Q10 peak absorption, compared to previously known compounds. Methods for making and using the aforementioned compositions also are provided.
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Lilling Herbert J.
NBTY, Inc.
Rothwell Figg Ernst & Manbeck P.C.
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