Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Reexamination Certificate
2005-05-31
2005-05-31
Chan, Christina (Department: 1644)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
C424S185100, C530S350000
Reexamination Certificate
active
06899875
ABSTRACT:
The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides and polynucleotides of the invention comprise amino acid and nucleic acid sequences of novel CD39-like gene and gene products.
REFERENCES:
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4501728 (1985-02-01), Geho et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4737323 (1988-04-01), Martin et al.
patent: 4837028 (1989-06-01), Allen
patent: 4946778 (1990-08-01), Ladner et al.
patent: 4959314 (1990-09-01), Mark et al.
patent: 4965188 (1990-10-01), Mullis et al.
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 2148851 (1996-10-01), None
patent: WO 90/03382 (1990-04-01), None
patent: WO 90/14148 (1990-11-01), None
patent: WO 91/09955 (1991-07-01), None
patent: WO 92/20808 (1992-11-01), None
patent: WO 94/12650 (1994-06-01), None
patent: WO 95/09248 (1995-04-01), None
patent: WO 96/30532 (1996-10-01), None
patent: WO 96/32471 (1996-10-01), None
patent: WO 00/04041 (2000-01-01), None
Ngo et al., in The Protein Folding Problem and Tertiary Structure Prediction, 1994, Merz, et al., (ed.), Birkhauser, Boston, MA, pp. 433-and 492-495.*
Mikayama et al, Molecular cloning and functional expression of a cDNA encoding gycosylation-inhibiting factor, Nov. 1993, Pro Natl. Acad. Sci, USA vol. 90: 10056-10060.*
Skolnick et al., From genes to protein structure and function: novel applications of computational approaches in the genomic era, Jan. 2000, Trends in Biotech. 18(1): 34-39.*
Attwood et al., The babel of bioinformatics, Oct. 2000, Science 290 (5491): 471-473.*
Hicks-Berger, C.A. et al., “Expression and Characterization of Soluble and Membrane-bound Human Nucleoside Triphosphate Diphosphohydrolase 6 (CD39L2),”J. Biol. Chem., 275(44):34041-34045 (2000).
Chadwick, B.P. et al., “Cloning and Mapping of a Human and Mouse Gene with Homology to Ecto-ATPase Genes,”Mammalian Genome, 8:668-672(1997).
Chadwick, B.P. et al. “cDNA Cloning and Chromosomal Mapping of a Mouse Gene with Homology to NTPases,”Mammalian Genome, 9:162-164 (1998).
Chadwick B.P. et al., “The CD39-like Gene Family: Identification of Three New Human Members (CD36L2, CD39L3, and CD39L4), Their Murine Homologues, and a Member of the Gene Family fromDrosophila melanogaster,” Genomics, 50:357-367 (1998).
Smith, T.M.. et al., “Cloning, Sequencing, and Expression of a Human Brain Ecto-Apyrase Related to Both the Ecto-ATPases and CD39 Ecto-Apyrases,”Biochim. Biophys Acta, 1386:65-78 (1998).
Adelman, J. P. et al., “In Vitro Deletional Mutagenesis for Bacterial Production of the 20,000-Dalton Form of Human Pituitary Growth Hormone,”DNA, 2(3):183-193 (1983).
Mulero, J.J. et al., “CD39-L4 Is a Secreted Human Apyrase, Specific for Hydrolysis of Nucleoside Disphosphates,”J. Biol. Chem., 274(29): 20064-20067(1999).
Altschul, S.F. et al., “Basic Local Alignment Search Tool,”J. Mol. Biol., 215:403-410 (1990).
Altschul, S.F., “A Protein Alignment Scoring System Sensitive at All Evolutionary Distances,”J. Mol. Evol., 36:290-300 (1993).
Anderson, W.F., “Human Gene Therapy,”Nature(Supp.), 392:25-30 (1998).
Asseline, U. et al., “Nucleic Acid-Binding Molecules with High Affinity and Base Sequence Specificity: Intercalating Agents Covalently Linked to Oligodeoxynucleotides,”Proc. Natl. Acad. Sci., USA, 81: 3297-3301 (1984).
Bayer, E.A. et al., “The Avidin-Biotin Complex in Affinity Cytochemistry,”Meth. Enzym., 62:308-315 (1979).
Beal, P.A. et al., “Second Structural Motif for Recognition of DNA by Oligonucleotide-Directed Triple-Helix Formation,”Science, 251:1360-1363 (1991).
Bonaldo, M. et al., “Normalization and Subtraction: Two Approaches to Facilitate Gene Discovery,”Genome Res., 6:791-806 (1996).
Boorstein et al., “Primer Extension Analysis of RNA,”Methods Enzymol., 180:347-369 (1989).
Breslauer, K.J. et al., “Predicting DNA Duplex Stability from the Base Sequence,”Proc. Natl. Acad. Sci., USA, 83: 3746-3750.
Broude, N.E. et al., “Enhanced DNA Sequencing by Hybridization,”Proc. Natl. Acad. Sci., USA, 91: 3072-3076 (1994).
Brumbaugh, J.A. et al, “Continuous, On-line DNA Sequencing Using Oligonucleotide Primers with Multiple Fluorophores,”Proc. Natl. Acad. Sci., USA, 85:5610-5614 (1988).
Burnstock, G., “The Past, Present and Future of Purine Nucleotides as Signalling Molecules,”Neuropharmacology, 36:1127-1139 (1997).
Cate, R.L. et al. “Genomic Southern Analysis with Alkaline-Phosphatase-Conjugated Oligonucleotide Probes and the Chemiluminescent Substrate AMPPD,”Genet. Anal. Tech. Appl., 8(3):102-106 (1991).
Cole, S.P.C. et al., “The EBV-Hybridoma Technique and It's Application to Human Lung Cancer,”Monoclonal Antibodies and Cancer Therapy, Alan R. Liss, Inc., pp. 77-96 (1985).
Communi, D. et al., “Cloning, Functional Expression and Tissue Distribution of the Human P2Y6Receptor,”Biochem. Biophys. Res. Com., 222:.303-308 (1996).
Cooney, M. et al., “Site-Specific Oligonucleotide Binding Represses Transcription of the Human c-myc Gene in Vitro,”Science, 15241:456-459 (1988).
Craig, M.E. et al., “Relaxation Kinetics of Dimer Formation by Self Complementary Oligonucleotides,”J. Mol. Biol., 62:383-401 (1971).
Dahlén et al., “Sensitive Detection of Genes by Sandwich Hybridization and Time-Resolved Fluorometry,”Mol. Cell. Probes(England), 1:159-168 (1987).
Daly, J. et al., “Direct Method for Determining Inorganic Phosphate in Serum with the CentrifiChem”,Clin. Chem., 18:263-265 (1972).
Dolinnaya, N.G. et al., “Site-directed Modification of DNA Duplexes by Chemical Ligation,”Nucleic Acids Research, (England), 16(9):3721-3738 (1988).
Dolinnaya, N.G. et al., “The use of BrCN for assembling modified DNA duplexes and DNA-RNA hybrids; comparison with water-soluble carbodiimide,”Nucleic Acids Res. (ENGLAND),19(11):3067-72 (1991).
Drmanac, R. et al., “ A calculation of fragment lengths from human DNA with 78 restriction enzymes: an aid for cloning and mapping,”Nucleic Acids Research, 14(11): 4691-4692 (1986).
Drmanac, R et al., Sequencing of Megabase Plus DNA by Hybridization: Theory of the Method,Genomics, 4:114-128 (1989).
Drmanac, R. et al., “Reliable Hybridization of Oligonucleotides as Short as Six Nucleotides,”DNA Cell Biol., 9:527-534 (1990).
Drmanac, R. et al., “An Algorithm for the DNA Sequence Generation from k-Tuple Word Contents of the Minimal Number of Random Fragments,”J. Biomol. Struct. Syn., 8(5):1085-1102 (1991).
Drmanac, R. et al., “Sequencing By Oligonucleotide Hyridization: A Promising Framework in Decoding of the Genome Program?”Proceedings of the First International Conference Electrophoresis Supercomputing Human Genome, Cantor et al., (Eds.), World Scientific Publishing Co., Singapore, pp. 47-59 (1991).
Drmanac, R. et al., “W (A or T) Sequences as Probes and Primers Suitable for Genomic Mapping and Fingerprinting,”Nucleic Acids Research, 19(21):5839-5842 (1991).
Drmanac, R. et al., “DNA Sequence Determination by Hybridization: A Strategy for Efficient Large-Scale Sequencing,”Science, 260(5114):1649-1652 (1993).
Drmanac, S. et al., “Processing of cDNA and Genomic Kilobase-Size Clones for Massive Screening, Mapping and Sequencing by Hybridization,”Biotechniques, 17:328-329, 332-336 (1994).
Dubyak, G. R. et al., “Signal Transduction via P2-Purinergic Receptors for Extracellular ATP and Other Nucleotides,”Am. J. Physiol. 34:C577-C606 (1993).
Duncan, C.H. et al., “Affinity Chromatography of a Sequence-Specific DNA Binding Protein using Teflon-link
Chadwick Brian Paul
Frischauf Anna-Maria
Chan Christina
Huynh Phuong N.
Nuvelo, Inc.
Polizotto Renee
LandOfFree
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