Methods and compositions for use in the treatment of...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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Details

C435S006120, C435S069100, C435S320100, C435S007210, C435S091200, C435S235100, C536S023100, C536S023400, C530S300000, C530S350000

Reexamination Certificate

active

06933108

ABSTRACT:
Methods and compositions are provided for at least slowing the progression of a filovirus mediated disease condition in a host. In the subject methods, an effective amount of an agent that at least reduces the amount of folate receptor mediated filovirus cell entry is administered to the host. The subject methods find use in both the prevention and treatment of filovirus associated disease conditions, including Marburg and Ebola-Zaire virus mediated disease conditions.

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Roberts et al. (1998) “Role of Individual N-Linked Glycosylation Sites in the Function and Intracellular Transport of the Human α Folate Receptor.”Archives of Biochemistry and Biophysics, vol. 351(2):227-235.
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