Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-05-24
2010-06-29
Lewis, Patrick T (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S023000, C514S025000
Reexamination Certificate
active
07745421
ABSTRACT:
The invention provides therapeutic methods and compositions for the prevention and treatment of Siglec-8 associated diseases and disorders such as asthma and allergic reactions. In particular, the invention provides methods and compositions for the prevention and treatment of diseases and disorders associated with Siglec-8 expressing cells in humans, as well as other animals, through the administration of one or more novel, carbohydrate-based compounds.
REFERENCES:
Hemmerich DDT (2001), vol. 6, pp. 27-35.
Jain et al. J. Am. Chem. Soc. (1994), vol. 116, pp. 12123-12124.
Komba, et al., “Synthesis of sialyl Lexganglioside analogues sulfated at C-6 of either the galactose or N-acetylglucosamine residues, and at both of the galactose and N-acetylglucosamine residues: probes for clarifying the real carbohydrate ligand of L-selection1,”Carbohydrate Research, (285), 1996, pp. C1-C8.
Dai, et al., “Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides”,Carbohydrate Research, (304), 1997, pp. 1-9.
Bochner Bruce S.
Schnaar Ronald L.
Corless Peter F.
Edwards Angell Palmer & & Dodge LLP
Lewis Patrick T
McKiernan Colleen
The Johns Hopkins University
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