Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-11-13
2007-11-13
Strzelecka, Teresa E. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S023100, C536S024300
Reexamination Certificate
active
10686466
ABSTRACT:
Methods for isothermal exponential amplification of a target polynucleotide are disclosed. The methods employ two transcription modules, the first module providing linear amplification resulting in RNA transcripts, and a second module providing for further (generally cyclical) amplification resulting in more RNA transcripts. In one aspect, the amplification of the first module is composite primer based. In a second aspect, the amplification of the first module is based on target switching to generate a primer extension product comprising a promoter sequence. In all aspects, the RNA transcripts of the first transcription module are subjected to further amplification by creating an intermediate product comprising a double stranded promoter region from which transcription can occur. The invention further provides compositions and kits for practicing said methods, as well as methods which use the amplification results.
REFERENCES:
patent: 4582788 (1986-04-01), Erlich
patent: 4683194 (1987-07-01), Saiki et al.
patent: 4786600 (1988-11-01), Kramer et al.
patent: 4876187 (1989-10-01), Duck et al.
patent: 4908385 (1990-03-01), Bar-Tana et al.
patent: 5011769 (1991-04-01), Duck et al.
patent: 5043272 (1991-08-01), Hartley
patent: 5130238 (1992-07-01), Malek et al.
patent: 5169766 (1992-12-01), Schuster et al.
patent: 5185243 (1993-02-01), Ullman et al.
patent: 5194370 (1993-03-01), Berninger et al.
patent: 5399491 (1995-03-01), Kacian et al.
patent: 5403711 (1995-04-01), Walder et al.
patent: 5409818 (1995-04-01), Davey et al.
patent: 5427911 (1995-06-01), Ruano
patent: 5427929 (1995-06-01), Richards et al.
patent: 5437990 (1995-08-01), Burg et al.
patent: 5480784 (1996-01-01), Kacian et al.
patent: 5508178 (1996-04-01), Rose et al.
patent: 5510270 (1996-04-01), Fodor et al.
patent: 5545522 (1996-08-01), Van Gelder et al.
patent: 5554516 (1996-09-01), Kacian et al.
patent: 5554517 (1996-09-01), Davey et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5589339 (1996-12-01), Hampson et al.
patent: 5595891 (1997-01-01), Rose et al.
patent: 5648211 (1997-07-01), Fraiser et al.
patent: 5654142 (1997-08-01), Kievits et al.
patent: 5660988 (1997-08-01), Duck et al.
patent: 5665545 (1997-09-01), Malek et al.
patent: 5679512 (1997-10-01), Laney et al.
patent: 5683879 (1997-11-01), Laney et al.
patent: 5710028 (1998-01-01), Eyal et al.
patent: 5716785 (1998-02-01), Van Gelder et al.
patent: 5731146 (1998-03-01), Duck et al.
patent: 5744308 (1998-04-01), Guillou-Bonnici et al.
patent: 5744312 (1998-04-01), Mamone et al.
patent: 5763178 (1998-06-01), Chirikjian et al.
patent: 5766849 (1998-06-01), McDonough et al.
patent: 5824517 (1998-10-01), Cleuziat et al.
patent: 5824518 (1998-10-01), Kacian et al.
patent: 5846710 (1998-12-01), Bajaj
patent: 5849547 (1998-12-01), Cleuziat et al.
patent: 5854033 (1998-12-01), Lizardi
patent: 5871697 (1999-02-01), Rothberg et al.
patent: 5876976 (1999-03-01), Richards et al.
patent: 5882867 (1999-03-01), Ullman et al.
patent: 5888779 (1999-03-01), Kacian et al.
patent: 5888819 (1999-03-01), Goelet et al.
patent: 5958681 (1999-09-01), Wetmur et al.
patent: 5962271 (1999-10-01), Chenchik et al.
patent: 5962272 (1999-10-01), Chenchik et al.
patent: 5965409 (1999-10-01), Pardee et al.
patent: 6004744 (1999-12-01), Goelet et al.
patent: 6004745 (1999-12-01), Arnold, Jr. et al.
patent: 6013431 (2000-01-01), Soderlund et al.
patent: 6027889 (2000-02-01), Barany et al.
patent: 6027923 (2000-02-01), Wallace
patent: 6030774 (2000-02-01), Laney et al.
patent: 6037152 (2000-03-01), Richards et al.
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6090591 (2000-07-01), Burg et al.
patent: 6107032 (2000-08-01), Kilger et al.
patent: 6132997 (2000-10-01), Shannon
patent: 6143495 (2000-11-01), Lizardi et al.
patent: 6218151 (2001-04-01), Cleuziat et al.
patent: 6251639 (2001-06-01), Kurn
patent: 6291170 (2001-09-01), Van Gelder et al.
patent: 6358712 (2002-03-01), Jarrell et al.
patent: 2001/0000077 (2001-03-01), Engelhardt et al.
patent: 2001/0041334 (2001-11-01), Rashtchian et al.
patent: 2002/0058270 (2002-05-01), Kurn
patent: 2002/0115088 (2002-08-01), Kurn
patent: 2002/0164628 (2002-11-01), Kurn
patent: 2003/0017591 (2003-01-01), Kurn
patent: 2003/0087251 (2003-05-01), Kurn
patent: 0 050 424 (1982-04-01), None
patent: 0 084 796 (1983-08-01), None
patent: 0 201 184 (1986-12-01), None
patent: 0 258 017 (1988-03-01), None
patent: 0 320 308 (1989-06-01), None
patent: 0 365 627 (1990-05-01), None
patent: 0 395 398 (1990-10-01), None
patent: 0 237 362 (1992-03-01), None
patent: 0 497 272 (1992-08-01), None
patent: 0 500 224 (1992-08-01), None
patent: 0 505 012 (1992-09-01), None
patent: 0 543 612 (1993-05-01), None
patent: 0 667 393 (1995-08-01), None
patent: 0 878 553 (1998-11-01), None
patent: 0 971 039 (2000-01-01), None
patent: 1 055 736 (2000-11-01), None
patent: 07-023799 (1995-01-01), None
patent: WO 88/02746 (1988-04-01), None
patent: WO 88/10315 (1988-12-01), None
patent: WO 92/15712 (1992-09-01), None
patent: WO 95/03426 (1995-02-01), None
patent: WO 97/04126 (1997-02-01), None
patent: WO 97/32040 (1997-09-01), None
patent: WO 98/01050 (1998-01-01), None
patent: WO 98/28443 (1998-07-01), None
patent: WO 99/18241 (1999-04-01), None
patent: WO 99/29901 (1999-06-01), None
patent: WO 99/37808 (1999-07-01), None
patent: WO 99/40219 (1999-08-01), None
patent: WO 99/42618 (1999-08-01), None
patent: WO 99/55912 (1999-11-01), None
patent: WO 00/08208 (2000-02-01), None
patent: WO 00/09745 (2000-02-01), None
patent: WO 00/28082 (2000-05-01), None
patent: WO 00/40715 (2000-07-01), None
patent: WO 00/52191 (2000-09-01), None
patent: WO 00/56925 (2000-09-01), None
patent: WO 00/70095 (2000-11-01), None
patent: WO 01/20035 (2001-03-01), None
patent: WO 01/23613 (2001-04-01), None
patent: WO 01/64952 (2001-09-01), None
patent: WO 01/73134 (2001-10-01), None
patent: WO 02/00938 (2002-01-01), None
patent: WO 02/28876 (2002-04-01), None
patent: WO 02/29117 (2002-04-01), None
patent: WO 02/48402 (2002-06-01), None
patent: WO 02/072772 (2002-09-01), None
patent: WO 02/103013 (2002-12-01), None
Ausubel et al. (eds.) (1995).Current Protocols in Molecular Biology. John Wiley & Sons, Inc., pp. iii-xii (Table of Contents).
Blanchard et al., (1996). “High-density oligonucleotide arrays.”Biosensors&Bioelectronics, 11:687-690.
Caruthers et al., (1987). “Chemical Synthesis of Deoxyoligonucleotides by the Phosphoramidite Method.”Methods In Enzymology 154:287-313.
DeRisi et al., (1996). “Use of a cDNA microarray to analyse gene expression patterns in human cancer.”Nature Genetics 14:457-460.
Flanagan et al., (1999). “A Cytosine Analog That Confers Enhanced Potency to Antisense Oligonucleotides,”Proc. Natl. Acad. Sci. U.S.A. 96(7):3513-3518.
Fodor et al., (1991). “Light-Directed, Spatially Adressable Parallel Chemical Synthesis.”Science 251:767-773.
Freshney (ed.) (1987)Animal Cell Culture. IRL Press: Oxford, pp. vii-xii (Table of Contents).
Gait (ed.) (1984)Oligonucleotide Synthesis: A Practical Approach. IRL Press: Oxford, pp. vii-xii (Table of Contents).
Guatelli et al., (1990). “Isothermal, In Vitro Amplification of Nucleic Acids by a Multienzyme Reaction Modeled After Retroviral Replication.”Proc. Natl. Acad. Sci. U.S.A. 87:1874-1878.
Innis et al. (eds.) (1990) PCR Protocols: A Guide to Methods and Applications, Academic Press, pp. v-x (Table of Contents).
Khrapko et al., (1991). “A method for DNA sequencing by hybridization with oligonucleotide matrix.”DNA Sequence I:375-388.
Kumar et al., (1998). “The First analogues of Locked Nucleic Acids: Phosphorothioate-LNA and 2′—Thio-LNA”Bioorg. Med. Chem. Lett. 8(16):2219-2222.
Lockhart et al., (1996). “Expression monitoring by hybridization to high-density oligonucleotide arrays.”Nature Biotechnology 14:1675-1680.
Marshall and Hodgson, (1998). “DNA chips: An array of possibilities.”Nature Biotechnol. 16:27-31.
Maskos and Southern, (
Nugen Technologies, Inc.
Strzelecka Teresa E.
Wilson Sonsini Goodrich & Rosati
LandOfFree
Methods and compositions for transcription-based nucleic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for transcription-based nucleic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for transcription-based nucleic... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3853659