Methods and compositions for topical delivery of retinoic acid

Details Methods and compositions for topical delivery of retinoic acid Methods and compositions for topical delivery of retinoic acid

1993-06-17

1999-09-21

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

514951, 514859, A61K 916

Patent

active

059551097

ABSTRACT:
Retinoic acid compositions intended for topical application are incorporated in novel formulations in which they are retained as impregnants inside the pores of porous solid particles or microspheres. The pores form a continuous network open to the exterior of the particles, permitting outward diffusion of the retinoic acid impregnant at a controlled rate depending on the pore size. The impregnated particles are prepared by impregnation of preformed particles with the retinoic acid.

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