Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1990-04-10
1990-11-06
Stone, Jacqueline
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 9463, 514363, 548126, A61K 37547, A61K 31415, C07D41704
Patent
active
049684949
ABSTRACT:
Certain Factor XIIIa inhibitor compounds have been discovered which have been found to be useful in the lysis of blood clots and thus adaptable for administration in thrombolytic therapy either alone or together with plasminogen activator.
REFERENCES:
patent: 4218476 (1980-08-01), Joensson et al.
patent: 4265898 (1981-05-01), Horstmann et al.
Bergmann et al, Science, vol. 220, Jun. 1983, pp. 1181-1183,
Claremon David A.
Friedman Paul A.
Remy David C.
Stern Andrew M.
Caruso Charles M.
Merck & Co. , Inc.
Robertson Alice O.
Stone Jacqueline
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