Methods and compositions for the treatment of neurodegeneration

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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Details

514660, 514674, 514654, 514316, 514315, A61K 3113, A61K 31445

Patent

active

058860517

ABSTRACT:
Methods and pharmaceutical compositions in unit dosage form for treating neurodegeneration in a human or non-human animal afflicted therewith wherein the active agent is a therapeutically effective amount of a polyamine having the formula: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R.sub.1 and R.sub.6 may be the same or different and are hydrogen, alkyl, hydrocarbyl aryl, hydrocarbyl aryl alkyl, cycloalkyl, or any of the foregoing wherein the alkyl chain is interrupted by at least one etheric oxygen atom;

REFERENCES:
patent: 4591605 (1986-05-01), Ray
patent: 5242947 (1993-09-01), Cherksey et al.

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