Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1994-12-29
1996-11-12
Rollins, John W.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424502, 514558, 514861, 514863, 514864, 514943, A61K 914, A61K 950, A61K 3700
Patent
active
055737811
ABSTRACT:
Methods and compositions are provided for the treatment of a host with a cellular proliferative disease, particularly a neoplasia. In the subject methods, a pharmaceutically acceptable, substantially anhydrous, injectable semi-solid composition which acts as a depot for a cytostatic agent, is administered to a lesion of the disease, particularly intralesionally. The subject compositions comprise a water immiscible, fatty acid ester matrix and a cytostatic agent.
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John W. Rollins Feb. 5, 1995.
Brown Dennis M.
Jones Richard E.
Maskiewicz Richard
Michaels Shawnya K.
Matrix Pharmaceutical, Inc.
Rollins John W.
Rowland Bertram I.
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