Methods and compositions for the treatment and prevention of...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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C424S009340, C424S093200, C424S093420, C424S165100, C424S184100, C424S185100, C424S190100, C514S04400A, C530S388200, C530S388210, C536S023700

Reexamination Certificate

active

07067135

ABSTRACT:
The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with,Staphylococcusspp., particularlyS. aureus.

REFERENCES:
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patent: WO 97 44349 (1997-11-01), None
patent: WO 99/32133 (1999-07-01), None
patent: WO 99 32133 (1999-07-01), None
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Lee.1998. Trends in Micrbiol. vol. 6(12):461-463.
Balaban et al., “Autocrine regulation of toxin synthesis byStaphylococcus aureas”Proc.Natl. Acad. Sci. USA(1995) 92:1619-1623.
Balaban et al., “Translation of RNAIII, theStaphylococcus aureas agrregulatory RNA molecule, can be activated by a 3′-end deletion”FEMS Microbiol. Letters(1995) 133:155-161.
Balaban et al., “Autoinducer of Virulence As a Target for Vaccine and Therapy AgainstStaphylococcus aereus”Science(1998) 280:438-440.
Ji, et al. “Cell Density Control of Staphylococcus Virulence Mediated by an Octapeptide Pheromone,”Proc. Natl. Acad. Sci. USA(1995) 92:12055-12059.
Mayville, et al. “Structure-Activity Analysis of Synthetic Autoinducing Thiolactone Peptides formStaphylococcus aureusResponsible for Virulence,”Proc. Natl. Acad. Sci. USA(1999) 96:1218-1223.

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