Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2002-09-27
2010-02-09
Gabel, Gailene R (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120, C435S007100, C435S007200, C435S007920, C435S038000, C435S971000, C435S973000, C436S063000, C436S518000, C436S523000, C436S524000, C436S528000, C436S537000, C436S010000, C436S056000, C436S164000, C436S172000
Reexamination Certificate
active
07659085
ABSTRACT:
Methods and compositions comprising immunoassays for the detection of antigens and antibodies in a sample are described. In particular, the present invention provides assays that are useful for the rapid and simultaneous detection of multiple different antigens and antibodies. In preferred embodiments, the assays include fluorescent labels of multiple wavelengths or intensities, which are used to label the antigens and antibodies directly and to label beads coated with molecules specific for the antigen or antibody. The detection of a fluorescence shift indicates the presence or identity of the antigen or antibody in the sample.
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Martinez et al., “A Flow Cytometric Opsonophagocytic Assay for Measurement of Functional Antibodies Elicited after Vaccination with the 23-Valent Pneumococcal Polysaccharide Vaccine”,Clinical and Diagnostic Laboratory Immunology, Jul. 1999, pp. 581-586, vol. 6, No. 4.
Carlone George M.
Martinez Joseph E.
Gabel Gailene R
Gifford Krass Sprinkle Anderson & Citkowski P.C.
The United States of America as represented by the Department of
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