Methods and compositions for the production of human transferrin

Details Methods and compositions for the production of human transferrin Methods and compositions for the production of human transferrin

1985-04-25

1991-06-25

Warren, Charles F.

Chemistry: molecular biology and microbiology

Vector, per se

435 91, 4351723, 43525233, 4353171, 435 691, 435 711, 536 27, C12N 1500, C12N 120, C12P 1934, C12P 2102, C07H 1512

Patent

active

050266519

ABSTRACT:
The present invention discloses the isolation and nucleic acid sequence of a cDNA recombinant plasmid insert which contains the entire coding sequence for the human transferrin protein. The predicted amino acid sequence of human transferrin is disclosed as well. The cDNA-bearing recombinant plasmid was selected from a human recombinant clone bank constructed in the plasmid pKT218, a derivative of pBR322. Also disclosed are proposed methods and compositions for constructing a recombinant expression vector whereby one may obtain expression of the recombinant human transferrin protein.

REFERENCES:
Schaeffer et al., Gene, vol. 56, pp. 109-116 (1987).
Blattner et al., Science, vol. 196, pp. 161-169.

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