Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Patent
1995-12-07
1998-10-27
Weddington, Kevin E.
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
514 29, 514 37, 514 39, 514 41, 514154, 514163, 514192, 514199, 514200, 514390, 514398, A61K 3324
Patent
active
058275436
ABSTRACT:
The subject invention encompasses methods for prevention and treatment of a human or lower animal subject having a urogenital disorder caused or mediated by one or more parasitic protozoa comprising administering to the subject bismuth and one or more antimicrobials. The subject invention also encompasses compositions comprising bismuth and one or more antimicrobials for the prevention and treatment of a human or lower animal subject having a urogenital disorder caused or mediated by one or more parasitic protozoa.
REFERENCES:
patent: 4049817 (1977-09-01), Laber et al.
patent: 4514421 (1985-04-01), Herschler
patent: 5221664 (1993-06-01), Berkowitz et al.
patent: 5256684 (1993-10-01), Marshall
Abstract from France Patent (2978) filed Oct. 1963.
M. Windholz et al., The Merek Index, 10th Ed. p. 882 abstract No. 6033 (1983).
Cavier, R., "Etude des proprieres parasiticides de quelques complexes bismuthiques de l'oxy-8 quinoleine", Annales pharmaceutiques francaises, 1973, 31, No. 4, pp. 173-178 (translation attached).
Pitlik, S., et al., "Cryptosporidial Cholecystitis", The New England Journal of Medicine, vol. 308, No. 16 (Apr. 21, 1983), p. 967.
Than, U Pe, et al., "The Alkaloids of Holarrhena Antidysenterica", Union of Burma Journal of Science and Technology, vol. 2, Dec. 1969, pp. 423-436.
Willard, F. L., et al., "Survey of Chemical Compounds Tested In Vitro Against Rumen Protozoa for Possible Control of Bloat", vol. 15, No. 5, Sep. 1967, pp. 1014-1019.
DuPont, H., et al., Symptomatic Treatment of Diarrhea With Bismuth Subsalicylate Among Students Attending a Mexican University, Gastroenterology, vol. 73, (1977), pp. 715-718.
DuPont, H., "Enteropathogenic Organisms: New Etiologic Agents and Concepts of Disease", Medical Clinics of North America, vol. 62, No. 5 (1978), pp. 945-960.
Wolfe, M., "The Treatment of Intestinal Protozoan Infections", Medical Clinics of North America, vol. 56, No. 3 (1982), pp. 707-720.
Journal of the American Medical Association, "Travelers' Diarrhea", vol. 253, No. 18 (1985), pp. 2700-2704.
DuPont, L., "Nonfluid Therapy and Selected Chemoprophylaxis of Acute Diarrhea", The American Journal of Medicine, vol. 78, Suppl. 6B (1985), pp. 81-90.
Johnson, P., et al., "Comparison of Loperamide With Bismuth Subsalicylate for the Treatment of Acute Traveler's Diarrhea", The Journal Of the American Medical Association, vol. 255, No. 6 (1986), pp. 757-760.
Steffen, R., "Anerkannte Prinzipien zur Prophylaxe und Therapie der Reisediarrhoe", Schweiz. med. Wschr. 116, Nr. 20 (1986), pp. 670-673 (translation provided).
DuPont, H., et al., "Prevention of Travelers' Diarrhea By the Tablet Formulation of Bismuth Subsalicylate", The Journal of the American Medical Association, vol. 257, No. 10 (1987), pp. 1347-1350.
White, N., "Drug Treatment and Prevention of Malaria", European Journal of Clinical Pharmacology, vol. 34 (1988), pp. 1-14.
D'Alessandro, A., "Amebiasis Then", American Journal of Tropical Medicine and Hygiene, vol. 41, No. 3, Suppl. (1989), pp. 38-39.
Steffen, R., "Worldwide Efficacy of Bismuth Subsalicylate in the Treatment of Travelers' Diarrhea", Reviews of Infectious Diseases, vol. 12, Suppl. 1 (1990), pp. S80-S86.
Long, E., et al., "Alga Associated with Diarrhea in Patients with Acquired Immunodeficiency Syndrome and in Travelers", Journal of Clinical Microbiology, vol. 28, No. 6 (1990), pp. 1101-1104.
Wolfe, M., "Acute Diarrhea Associated With Travel", The American Journal of Medicine, vol. 88, Suppl. 6A (1990), pp. 34S-37S.
Qadri, S.M.H., "Infectious Dairrhea: Managing a Misery that is Still Worldwide", Postgraduate Medicine, vol. 88, No. 5 (1990), pp. 169-184).
Farthing, M.J.G., et al., "Treatment and Prevention of Travellers' Diarrhoea", Gastroenterology International, vol. 5, No. 3 (1992), pp. 162-175.
Zinsser Microbiology, 20th ed., Appleton & Lange (1992), pp. 1161-1173.
Arduino, R., et al., "Travellers' Diarrhoea", Bailliere's Clinical Gastroenterology, vol. 7, No. 2 (1993), pp. 365-385.
Chak, A., et al., "Traveler's Diarrhea", Gastroenterology Clinics of North America, vol. 22, No. 3 (1993), pp. 549-561.
American Health Consultants, "Cryptosporidiosis in Milwaukee", vol. 12, No. 15 (1993), pp. 113-115.
Wittner, M., et al., "Parasitic Infections in AIDS Patients: Cryptosporidiosis, Isosporiasis, Microsporidiosis, Cyclosporiasis", Infectious Disease Clinics of North America, vol. 7, No. 3 (1993), pp. 569-586.
Weber, R., et al., "Disseminated Microsporidiosis Due to Encephalitozoon Hellem: Pulmonary Colonization, Microhematuria, and Mild Conjunctivitis in a Patient with AIDS", Clinical Infectious Diseases, vol. 17 (1993), pp. 415-419.
Kuhls, T., "Protozoal Infections of the Intestinal Tract in Children", Advances in Pediatric Diseases, vol. 8 (1993), pp. 177-202.
Scott, D., et al., "Treatment of Gastrointestinal Infections", Bailliere's Clinical Gastroenterology, vol. 7, No. 2 (1993), pp. 477-499.
Martindale, The Extra Pharmacopoeia, "Gastro-intestinal Agents", Thirtieth Ed., The Pharmaceutical Press (1993), p. 872.
Health, "Are Milwaukee-Type Parasites Floating in My Drinking Water?" (1993), p. 14.
Sun, T., et al., "Intestinal Microsporidiosis: Report of Five Cases", Annals of Clinical and Laboratory Science, vol. 24, No. 6 (1994), pp. 521-532.
American Drug Index, 38th Ed. (1994), pp. 568-569.
Upcroft, P., "Multiple Drug Resistance in the Pathogenic Protozoa", Acta Tropica, vol. 56 (1994), pp. 195-212.
Herwaldt, B., et al., "Infections with Intestinal Parasites in Peace Corps Volunteers in Guatemala", Journal of Clinical Microbiology (1994), pp. 1376-1378.
Physicians' Desk Reference, 48th Ed. (1994), pp. 724-726.
Jernigan, et al., "Parasitic Infections of the Small Intestine", Gut, vol. 35, No. 3 (1994), pp. 289-293.
Fritsche, T., et al., "Introduction to Diagnostic Parasitology: Biologic, Clinical, and Laboratory Considerations", Manual of Clinical Microbiology, Sixth Ed., ASM Press (1995), pp. 1141-1144.
Chevalier, C., et al., "Bilan Des Antiparasitaires A Usage Veterinaire: Antihelminthiques, Anticoccidiens, Antifongiques, Ectoparasiticides" (translation attached), Laboratory of Therapeutic Chemistry, College of Pharmacy , 37042 Tours Cedex, pp. 624-630.
Mohl Douglas C.
Poland Mary Catherine
Rasser Jacobus C.
The Procter & Gamble & Company
Weddington Kevin E.
LandOfFree
Methods and compositions for the prevention and treatment of uro does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for the prevention and treatment of uro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for the prevention and treatment of uro will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1612137