Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-09-19
2006-09-19
Peselev, Elli (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S006400
Reexamination Certificate
active
07109177
ABSTRACT:
The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3′ of the sugar moiety or modified or unmodified alkyl-aromatic ring substitutions at the C-4′ of the sugar moiety. It also discloses novel methods for the preparation of sugar substrates and methods for the preparation of anthracycline antibiotics. These anthracycline analogs show high cytotoxicity in vitro against several tumor cell lines.
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patent: 4355026 (1982-10-01), Umezawa et al.
patent: 5319077 (1994-06-01), Kinzy
patent: 5625043 (1997-04-01), Priebe et al.
International Search Report dated Oct. 5, 2000.
Fokt Izabella
Grynkiewicz Grzegorz
Krawczyk Marta
Perez-Soler Roman
Priebe Waldeman
Fulbright & Jaworski L.L.P.
Houston Pharmaceuticals, Inc.
Peselev Elli
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