Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1986-04-01
1991-07-09
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
424 858, 435 693, 4351722, 43524027, 435975, 436501, 436503, 436536, 436543, 436547, 436548, 436 64, 436808, 436813, 530387, 530395, 530403, 530413, 530417, 530828, 935107, 935110, G01N 3353, G01N 33567, C07K 1514, C07K 114
Patent
active
050305590
ABSTRACT:
Disclosed are monoclonal antibodies which react with human tumor cells, particularly metastatic human tumor cells, but not with normal human tissues tested. The monoclonal antibodies are prepared against a 580 kilodalton glycoprotein antigen, designated gp580, which is isolated from either rat or human tumor cells. Methods for isolating the glycoprotein antigen are disclosed as well. Moreover, techniques are disclosed for utilizing these antibodies both in the detection and in the prevention of human tumor lesions.
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Nicolson Garth L.
North Susan M.
Steck Peter A.
Board of Regents , The University of Texas System
Hoffer Florina B.
Kepplinger Esther L.
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