Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi
Patent
1997-04-11
1999-10-19
Achutamurthy, Ponnathapura
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Fungi
435189, 43525421, 435325, 435410, 4353201, 536 231, 536 232, 536 237, 536 2374, 536 2432, C12N 116, C07H 2104
Patent
active
059688092
ABSTRACT:
The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to gamma-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising a desaturase gene, and recombinant host microorganism or animal expressing increased levels of a desaturase are described. Methods for desaturating a fatty acid and for producing a desaturated fatty acid by expressing increased levels of a desaturase are disclosed. Fatty acids, and oils containing them, which have been desaturated by a desaturase produced by recombinant host microorganisms or animals are provided. Pharmaceutical compositions, infant formulas or dietary supplements containing fatty acids which have been desaturated by a desaturase produced by a recombinant host microorganism or animal also are described.
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Chaudhary Sunita
Huang Yung-Sheng
Knutzon Deborah
Mukerji Pradip
Thurmond Jennifer
Abbot Laboratories
Achutamurthy Ponnathapura
Calgene Inc.
Nashed Nashaat T.
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