Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-01-24
2009-06-30
Tsang, Cecilia (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C530S300000, C530S344000, C530S350000, C530S412000, C435S069100, C435S069200, C435S069700, C435S071100, C435S071300
Reexamination Certificate
active
07553832
ABSTRACT:
The present invention relates to compositions (i.e., various organic small molecules as exemplified herein) and methods for the inhibition of protein splicing and especially relates to the inhibition of protein autosplicing of intein-containing proteins. Additionally, the present invention relates to the use of the inhibitors of protein splicing of the invention for the treatment of various diseases including but not limited to tuberculosis. Furthermore, the invention provides the first instance of small molecule inhibitors of protein splicing with drug-like characteristics.
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Boston Biomedical Research Institute
Bradley Christina Marchetti
Farrell Kevin M.
Pierce Atwood LLP
Tsang Cecilia
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