Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2005-03-10
2010-11-23
Kelly, Robert M (Department: 1633)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C424S184100, C424S198100, C530S387100, C530S300000
Reexamination Certificate
active
07837993
ABSTRACT:
The regenerative potential of aged stem cells is enhanced by activation of the Notch signaling pathway and/or inhibition of TGF-β signaling pathway. Stem cells in aged tissues are capable of proliferation and tissue regeneration, but in their native setting are not provided with the appropriate signals to do so. By administering tissue regenerating agents, organ stem/progenitor cells are provided with the appropriate signals to regenerate the corresponding differentiated tissues.
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Conboy Irina M.
Conboy Michael J.
Rando Thomas A.
Hozicevic, Field & Francis LLP
Kelly Robert M
Sherwood Pamela J.
The Board of Trustees of the Leland Stanford Junior University
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