Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-06-13
2006-06-13
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S041000, C435S068100, C435S069700, C435S069900, C435S071100
Reexamination Certificate
active
07060461
ABSTRACT:
Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed.
REFERENCES:
patent: 2003/0086918 (2003-05-01), Lima et al.
Varshavsky, A. Ubiquitin Fusion Technique and its Descendants. Methods in Enzymology 327:578-593, 2000.
Saitoh, H., et al., “SUMO-1: wrestling with a new ubiquitin-related modifer”, Trends Biochem. Sci. 22:374-6 (1997).
Johnson, E.S., et al., “The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer”, EMBO Journal, 16: 5509-5519 (1997).
Tanaka, K., et al., “Characterization of a Fission Yeast SUMO-1 Homologue, Pmt3p, Required for Multiple Nuclear Events, Including the Control of Telomere Length and Chromosome Segregation”, Molecular and Cellular Biology, 19: 8660-8672 (1999).
Li, S-J, et al, “The Yeast ULP2 (SMT4) Gene Encodes a Novel Protease Specific for the Ubiquitin-Like Smt3 Protein”, Molecular and Cellular Biology 20: 2367-2377 (2000).
Ichimura, Y., et al., “A ubiquitin-line system mediates protein lipidation”, Nature 408: 488-492, (2000).
Li, S-J., et al., “A new protease required for cell-cycle progression in yeast”, Nature 398: 246--251, (1999).
Mossessova, E., et al., “Ulp1-SUMO Crystal Structure and Genetic Analysis Reveal Conserved Interactions and a Regulatory Element Essential for Cell Growth in Yeast”, Molecular Cell, 5: 865-876 (2000).
Yeh, E.T.H., et al., “Ubiquitin-like proteins: new wines in new bottles”, Gene 248: 1-14 (2000).
Baker, R.T., “Protein expression using ubiquitin fusion and cleavage”, Current Opinion in Biotechnology, vol. 7: pp. 541-546, (1996).
Power, R.F., et al., “High Level Expression of a Truncated Chicken Progesterone Receptor inEscherichia coli”, The Journal of Biological Chemistry, vol. 265: p. 1419-1424 (1990).
Bayer, P., et al., “Structure Determination of the Small Ubiquitin-related Modifier SUMO-1”, Journal of Molecular Biology, vol. 280: pp. 275-286 (1998).
Liu, Q., et al., “The Binding Interface between an E2 (UBC9) and a Ubiquitin Homologue (UBL1)”, The Journal of Biological Chemistry, vol. 274: pp. 16979-16987, (1999).
Malakhov, M.P., et al., “SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins”, Journal of Structural and Fuctional Genomics, vol. 5: pp. 75-86, (2004).
Butt Tauseef R.
Malakhov Michael P.
Malakhova Oxana A.
Tran Hiep T.
Weeks Steven D.
Dann Dorfman Herrell and Skillman
Guzo David
Lambertson David
Lifesensors, Inc.
Netter, Jr. Robert C.
LandOfFree
Methods and compositions for protein expression and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for protein expression and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for protein expression and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3655296