Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Oxidoreductases
Reexamination Certificate
2011-07-05
2011-07-05
Fetterolf, Brandon J (Department: 1628)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Oxidoreductases
C514S047000, C514S048000
Reexamination Certificate
active
07972595
ABSTRACT:
Methods and compositions for protecting and treating a muscarinic receptor in a subject in need thereof from dysfunction not resulting from oxidative stress, toxic actions of metals or metal ions, or infectious agents by administering a pyrophosphate analog.
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Fawcett, John R. et al.; “Brain Research 850 (2002) 10-20: Research Report: Inactivation of the human brain muscarinic acetylcholine receptor by axidative damage catalyzed by a low molecular weight endogenous inhibitor from Alzheimer's brain is prevented by pyrophosphate analogs, bioflavonoids and other antioxidants”; Elsevier Science B.V.; www.elsevier.com/locate/bres; US 2002.
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Frey II, William H. et al.; “Brain Research 714 (1996) 87-94: Endogenous Alzheimer's brain factor and oxidaized glutathione inhibit antagonist binding to the muscarinic receptor”; Elsevier Science B.V.; US 1996.
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Fawcett John Randall
Frey, II William H.
Altera Law Group LLC
Fetterolf Brandon J
HealthPartners Research Foundation
Ricci Craig
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