Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1994-08-03
1996-10-01
Fleisher, Mindy
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530300, 530402, 530409, 435 681, 435 691, 435 701, 435 711, C07K 1400, C07K 700, C07K 102, C07K 104
Patent
active
055612210
ABSTRACT:
Disclosed are 1) compositions comprising isolated monomeric subunits of chaperonin-60 or truncated fragments thereof that promote the folding of a polypeptide chain in vitro, 2) monomeric subunits of chaperonin-60 or truncated fragments thereof, immobilized on a solid surface, that promote also the folding of a polypeptide chain in vitro, 3) methods for preparing and/or immobilizing the monomeric subunits of chaperonin-60 or truncated fragments thereof, and 4) methods for folding polypeptide chains, specifically polypeptide chains expressed in a heterologous expression system, in vitro using the monomeric subunits of chaperonin-60 or truncated fragments thereof.
REFERENCES:
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Konishi Jin
Taguchi Hideki
Yoshida Masasuke
Degen Nancy J.
Fleisher Mindy
Nippon Oil Company Limited
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