Surgery – Means for introducing or removing material from body for... – Material introduced into and removed from body through...
Patent
1988-06-08
1989-10-03
Rosenbaum, C. Fred
Surgery
Means for introducing or removing material from body for...
Material introduced into and removed from body through...
514912, A61M 3106
Patent
active
048713503
ABSTRACT:
Novel methods and compositions are provided for preventing secondary cataracts. A cytotoxic agent is employed which is introduced into the anterior chamber of the eye to inhibit proliferation of remnant lens epithelial cells after extracapsular cataract extraction. Desirably a non-cytotoxic agent cross-reactive with the cytotoxic agent is introduced prior to introduction of the cytotoxic agent. The agents can be provided as kits.
REFERENCES:
patent: 4307082 (1981-12-01), Rosenberg
patent: 4340535 (1982-07-01), Voisin et al.
patent: 4342828 (1982-08-01), Takaku et al.
patent: 4349528 (1982-09-01), Koprowski et al.
patent: 4363758 (1982-12-01), Musuho et al.
patent: 4379145 (1983-04-01), Musuho et al.
patent: 4432751 (1984-02-01), Emery et al.
patent: 4657930 (1987-04-01), Emery et al.
patent: 4661347 (1987-04-01), Muller-Eberhard
patent: 4665089 (1987-05-01), Siezen et al.
patent: 4778815 (1988-10-01), Cash
patent: 4778828 (1988-10-01), Palmai et al.
patent: 4797422 (1989-01-01), Testa
patent: 4814275 (1989-03-01), Durda et al.
patent: 4826872 (1989-05-01), Terao et al.
Blythman et al., "Immunotoxins: Hybrid Molecules of Monsclonal Antibodies and a Toxin Subunit Specifically Kill Tumour Cells", Nature, vol. 290, pp. 145-146, 1981.
Youle, "Antibody Linked to Ricin is a Potent All-Type-Specific Toxin", Proc. Natl. Sci., USA, vol. 77, No. 9, pp. 5483-5486, 9/80.
Gilliland et al., "Chimeric Toxins", Proc. Natl. Acad. Sci. USA, vol. 75, No. 11, pp. 5319-5323, Nov. 1978.
Szoka et al., "Procedure for Preparation of Lipisones", Proc. Natl. Acad. Sci. USA, vol. 75, No. 9, pp. 4194-4198, Sep. '78.
Campbell, "Monoclonal Antibody Technology", Laboratory Techniques in Biochemistry and Molecular Biology, vol. 13, pp. 16-25, 1986.
Olsnes et al., "Diff. Biol. Properties of the 2 Constituent Peptide Chains of Recin . . .", Biochemistry, vol. 12, No. 16, 1973, pp. 3121-3126.
Mussuho et al., "Prep. of a Hybrid of Fragment Fab' of Antibody and Fragment A of Diptheria Toxin and Its Cytotoxicity", Biochemical and Biophysical Research Communications, vol. 90, No. 1, 1979, pp. 320-326.
Heath et al., "Anti-Body Targeted Liposomes", Proc. Natl. Sci. USA, vol. 80, pp. 1377-1381, 3/83.
Russell et al., "The Development of a Monosclonal Antibody to a Human Gamma Crystallin", Current Eye Research, vol. 3, No. 11, pp. 1329-1335, 1984.
Kincses et al., "Experimental Production of Antibodies Against Cataractous Human Lens", Acta. Medica. Acad. Sci., vol. 31(1-2), pp. 9-13, 1974.
Nissen et al., "Antibodies to Lens Antigen in Cataract and After Cataract Surgery", British J. of Ophthalmology, vol. 65, pp. 63-66, 1981.
Cole et al., "Enzymatic Zonulolysis and Cryoextraction of Cataracts", International Surgery, vol. 50, No. 3, pp. 242-244, Sep. 1968.
Kelleher Peter J.
Lam Dominic M-K.
Baylor College of Medicine
Rae-Venter Barbara
Rose Sharon
Rosenbaum C. Fred
Rowland Bertram I.
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