Methods and compositions for pathogen detection using...

Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence

Reexamination Certificate

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C436S164000, C436S169000, C436S171000

Reexamination Certificate

active

08003404

ABSTRACT:
Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification.

REFERENCES:
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Kaufman et al. “Green fluorescent protein (GFP) as a vital marker for pathogenic development of the dermatophyte Trichophyton mentagrophytes”, Microbiology, 2004, v. 150, pp. 2785-2790.
Kim, I-B; Phillips, R; Bunz, UHF. Carboxylate Group Side-Chain Density Modulates the pH-Dependent Optical Properties of PPEs. Macromolecules 2007 40 (15), 5290-5293; published on Web Jun. 21, 2007.
Fialkowski, M; Bishop, KJM; Chubukow, VA; Campbell CJ; Grzbowski, BA. Architecture and Evolution of Organic Chemistry. Angew. Chem. Int. Ed. 2005, 44, pp. 7263-7269.
Bishop KJM; Klajn, R; Grzbowski, BA. The Core and Most Useful Molecules in Organic Chemistry. Angew. Chem. Int. Ed. 2006, 45, pp. 5348-5354.
De, M; Rana, S; Akpinar, H; Miranda, OR; Arvizo, RR; Bunz, UHF; Rotello, VM. Sensing of Proteins in human serum using conjugates of nanoparticles and green fluorescent protein. Nature Chemistry, vol. 1, Sep. 2009, pp. 461-465.
Bajaj, A; Miranda, OR; Kim, I-B; Phillips, RL; Jerry, DJ; Bunz, UHF. Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays. PNAS, Jul. 7, 2009, vol. 106, No. 27, pp. 10912-10916.

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