Methods and compositions for modulating somatolactogenic...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S004000, C530S350000

Reexamination Certificate

active

07105306

ABSTRACT:
Compositions containing cyclophilin B, mutants of cyclophilin B or inhibitors of cyclophilin B and methods of using these compositions to modulate somatolactogenic function are provided.

REFERENCES:
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patent: WO 9967288 (1999-12-01), None
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Ryczyn et al., Role of Cyclophilins in Somatolactogenic Action, 2000, Annals New York Academy of Sciences, vol. 917, pp. 514-521.
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Mariller et al., “Involvement of the N-terminal part of cyclophilin B in the interaction with specific Jurkat T-cell binding sites”,Biochemical Journal1996 317:571-576.
Mertani et al., “Cellular Expression of Growth Hormone and Prolactin Receptors in Human Breast Disorders”,Int. J. Cancer Pred. Oncol.1998 79:202-211.
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Price et al., “Human cyclophilin B:A second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence”,Proc. Natl. Acad. Sci. USA1991 88:1903-1907.

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