Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-08-07
2007-08-07
Salimi, Ali R. (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S005000, C435S069100
Reexamination Certificate
active
10903334
ABSTRACT:
This invention provides methods for identifying novel SHMT modulators. The methods comprise first screening test agents for modulators of p38 activity and then further screening the identified modulating agents for modulators of SHMT enzyme activity. The invention further provides methods and pharmaceutical compositions for modulating cellular proliferation and for treating tumors using the novel SHMT modulators.
REFERENCES:
patent: 6514719 (2003-02-01), Bird et al.
Kim Sungjoon
Shah Kavita
Genomics Institute of the Novartis Research Foundation
Salimi Ali R.
Smith Timothy L.
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