Methods and compositions for modulating cell proliferation

Details Methods and compositions for modulating cell proliferation Methods and compositions for modulating cell proliferation

2007-08-07

2007-08-07

Salimi, Ali R. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S005000, C435S069100

Reexamination Certificate

active

10903334

ABSTRACT:
This invention provides methods for identifying novel SHMT modulators. The methods comprise first screening test agents for modulators of p38 activity and then further screening the identified modulating agents for modulators of SHMT enzyme activity. The invention further provides methods and pharmaceutical compositions for modulating cellular proliferation and for treating tumors using the novel SHMT modulators.

REFERENCES:
patent: 6514719 (2003-02-01), Bird et al.

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